ArticleCureus2025
Transvaginal Needle Biopsy for the Diagnosis of Radiation-Induced Angiosarcoma in Cervical Cancer: Utility and Role of Next-Generation Sequencing.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Concurrent chemoradiotherapy (CCRT) is a common treatment for advanced cervical cancer, and angiosarcoma rarely occurs at the irradiated site. We report a case of angiosarcoma diagnosed via a transvaginal ultrasound-guided needle biopsy of a mass in the rectovaginal space, which developed five years after CCRT in a patient with stage IIIB cervical cancer. The biopsy specimen was analyzed using next-generation sequencing (NGS), which identified relevant somatic genetic mutations. This case highlights the value of needle biopsy as a useful diagnostic tool and its potential role in guiding treatment decisions.
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