Evidence map›Paper›PMID 40575160›Full record

ArticleFrontiers in oncology2025

Diagnostic performance of pre-procedure endoscopic biopsies in predicting the histology of gastric lesions undergoing ESD.

Qin Xu, Jinlei Yang, Zhenwang Shi, Dong Fang, Deming Bao, Liming Wang

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qin Xu *Department of Gastroenterology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China.
Jinlei Yang *Department of Thoracic Surgery, The First People's Hospital of Hefei, The Third Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhenwang ShiDepartment of Gastroenterology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China.
Dong FangDepartment of Gastroenterology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China.
Deming BaoDepartment of Gastroenterology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China.
Liming WangDepartment of Gastroenterology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer remains one of the most lethal malignancies worldwide. Endoscopic submucosal dissection (ESD), a minimally invasive procedure that has become the gold standard for early-stage gastric cancer management, demonstrates both diagnostic and therapeutic utility. With advancing ESD techniques and expanded clinical applications, discrepancies between preoperative biopsy findings and post-resection pathology evaluations have become increasingly evident in clinical practice. This retrospective analysis of 113 ESD-treated patients employed systematic comparative methods to quantify diagnostic discrepancies between initial biopsy interpretations and definitive histopathological assessments, while identifying critical contributing factors. Multivariate analysis revealed three independent predictors of histopathological discrepancies including lesion location, lesions exhibiting type IIc morphology and elevated Kyoto Gastric Cancer Risk Scores. These findings provide robust statistical evidence for refining preoperative risk stratification protocols, ultimately optimizing clinical outcomes in precision endoscopy.

Indexed as

differential analysisESDgastric cancerKGCRSpreoperative biopsy

Identifiers

PMID40575160
PMCPMC12197940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.