Evidence map›Paper›PMID 40575087›Full record

ReviewChemical & biomedical imaging2025

Nonlight-Driven Aggregation-Induced Emission Luminogens for Bioimaging and Theranostics.

Yong Tian, Weigeng Huang, Zhijia Sheng, Dingyuan Yan, Dong Wang, Ben Zhong Tang

Abstract readReview
In one paragraph

Review in Chemical & biomedical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yong TianCenter for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, Shenzhen University, Shenzhen 518060, China.
Weigeng HuangCenter for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, Shenzhen University, Shenzhen 518060, China.
Zhijia ShengCenter for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, Shenzhen University, Shenzhen 518060, China.
Dingyuan YanCenter for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, Shenzhen University, Shenzhen 518060, China.
Dong WangCenter for AIE Research, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, Shenzhen University, Shenzhen 518060, China.ORCID https://orcid.org/0000-0001-5137-0771
Ben Zhong TangSchool of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong (CUHK-Shenzhen), Shenzhen, Guangdong 518172, China.ORCID https://orcid.org/0000-0002-0293-964X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aggregation-induced emission luminogens (AIEgens) have been prosperously developed and applied in the fields of optical imaging and theranostics since its establishment. Nowadays, AIEgens can fulfill nearly all requirements in optical imaging and theranostics with emission spectra ranging from visible to near-infrared wavelengths. Although a variety of AIEgens with varying wavelengths and functionalities have been continuously designed, their performance is heavily dependent on the use of conventional light sources, such as xenon lamps and lasers, which severely hinder further applications due to limited penetration depth and background autofluorescence in biological tissues. To mitigate these limitations and maximize the potential of AIEgens, unconventional excitation sources such as chemical energy, ultrasound, and X-ray offer effective alternatives that circumvent the drawbacks associated with traditional light-based constant excitation. In this Review, we introduce the fundamental principles governing the combination of unconventional excitation sources with AIEgens, highlight recent advancements in using AIEgens excited by these unconventional sources for bioimaging and theranostics, and discuss current challenges and future perspectives aimed at advancing the biomedical applications of AIEgens.

Indexed as

aggregation-induced emissionchemiluminescencephototheranosticsultrasoundX-ray

Identifiers

PMID40575087
PMCPMC12188483

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.