ArticleInnovation in aging2025
Chasing the Pendulum: The Past, Present, and Future of Opioids and Older Adults.
Article in Innovation in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- One crisis, many ages: investigating opioid use disorder across the life course.Innovation in aging · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The management of pain in older adults has been profoundly shaped by shifting attitudes toward acute and chronic opioid therapy. Historically, opioids have been recognized as highly effective for acute and cancer-related pain, but their use in chronic non-cancer pain, especially among older adults, remains controversial due to concerns about addiction, safety, and efficacy. Over recent decades, increased opioid prescribing has coincided with a dramatic rise in opioid misuse, addiction, and overdose deaths, prompting renewed scrutiny of prescribing practices and regulatory responses. This article traces the historical "pendulum" of opioid policy and practice, examines the unique challenges faced by older adults-including heightened vulnerability to adverse effects and polypharmacy-and highlights the ongoing debate between ensuring adequate pain relief and minimizing harm. It also explores best practices and emerging approaches, such as patient-centered care and the integration of non-opioid therapies, and calls for a balanced, evidence-based framework that addresses both the legitimate needs of older adults in pain and the societal imperative to reduce opioid-related harms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.