Evidence map›Paper›PMID 40575017›Full record

ArticleInnovation in aging2025

Chasing the Pendulum: The Past, Present, and Future of Opioids and Older Adults.

Fred Rottnek

Abstract read
In one paragraph

Article in Innovation in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Fred RottnekSSM Health/Saint Louis University School of Medicine, Family and Community Medicine, St. Louis, Missouri, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of pain in older adults has been profoundly shaped by shifting attitudes toward acute and chronic opioid therapy. Historically, opioids have been recognized as highly effective for acute and cancer-related pain, but their use in chronic non-cancer pain, especially among older adults, remains controversial due to concerns about addiction, safety, and efficacy. Over recent decades, increased opioid prescribing has coincided with a dramatic rise in opioid misuse, addiction, and overdose deaths, prompting renewed scrutiny of prescribing practices and regulatory responses. This article traces the historical "pendulum" of opioid policy and practice, examines the unique challenges faced by older adults-including heightened vulnerability to adverse effects and polypharmacy-and highlights the ongoing debate between ensuring adequate pain relief and minimizing harm. It also explores best practices and emerging approaches, such as patient-centered care and the integration of non-opioid therapies, and calls for a balanced, evidence-based framework that addresses both the legitimate needs of older adults in pain and the societal imperative to reduce opioid-related harms.

Indexed as

AnalgesiaHarm reductionOverdosePainPrescription medications

Identifiers

PMID40575017
PMCPMC12201998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.