Trial reportBrain communications2025
Information processing speed modulation by electrical brain stimulation in multiple sclerosis: towards individually tailored protocols.
Trial report in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017-2025: An update) - endorsed by the European Society for Brain Stimulation (ESBS) and by the International Federation for Clinical Neurophysiology (IFCN).Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Information processing speed is a core cognitive process, highly relevant in everyday life and the most frequent and disabling cognitive symptom in patients with relapsing multiple sclerosis. Correlational evidence from brain imaging suggests involvement of the superior parietal lobe in the speed component of information processing, thereby providing a neurobiological foundation for neuromodulatory interventions. By using regionally specific, focalized transcranial direct current stimulation (tDCS) in healthy individuals and patients with relapsing multiple sclerosis, we provide causal evidence for superior parietal lobe involvement in information processing speed and identified a clinically relevant predictor of tDCS response in patients with relapsing multiple sclerosis. The study employed a registered, randomized, sham tDCS-controlled, three-way-blinded, cross-over trial and a mixed-factors design with eight arms [between-subjects: group (patients/healthy controls;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.