Evidence map›Paper›PMID 40574971›Full record

ArticleBrain communications2025

Glycine-to-aspartic acid mutation at codon 51 in

Stephen West, Ammar Natalwala, Karamjit Singh Dolt, Douglas J Lamont, Melanie McMillan, Kelvin Luk, Tomoji Mashimo, Tilo Kunath

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephen WestCentre for Regenerative Medicine, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, UK.
Ammar NatalwalaCentre for Regenerative Medicine, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, UK.
Karamjit Singh DoltCentre for Regenerative Medicine, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, UK.ORCID https://orcid.org/0000-0002-0584-7505
Douglas J LamontFingerPrints Proteomics Facility, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Melanie McMillanCentre for Reproductive Health, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, UK.
Kelvin LukDepartment of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Alzheimer's Disease Core Center, Institute on Aging, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104-2676, USA.ORCID https://orcid.org/0000-0002-6591-6269
Tomoji MashimoDivision of Animal Genetics, Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.
Tilo KunathCentre for Regenerative Medicine, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, UK.ORCID https://orcid.org/0000-0002-8805-7356

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Point mutations in the

Indexed as

G51D mutationlewy pathologyproteomicssynaptic dysfunctionα-synucleinopathies

Identifiers

PMID40574971
PMCPMC12198753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.