Evidence map›Paper›PMID 40574754›Full record

ArticleTranslational neuroscience2025

Antidepressant and neuromodulatory potential of hydroalcoholic extract of

Km Kajal, Tarique Anwer, Ankit Verma, Mohammad Firoz Alam, Saeed Alshahrani, Muhanad Alhujaily, Mohammed Naffaa Alruwaili, Ali Assiry, Abdullah Saleh Salem Alrashah

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Km KajalDepartment of Pharmacy, HIMT College of Pharmacy, Dr. A.P.J Abdul Kalam Technical University (AKTU), Knowledge Park 1, Greater Noida, Gautam Budh Nagar, U.P., 201310, India.
Tarique AnwerDepartment of Public Health, College of Applied Medical Sciences, University of Bisha, P.O. Box 225, Bisha, 67714, Saudi Arabia.
Ankit VermaDepartment of Pharmacy, HIMT College of Pharmacy, Dr. A.P.J Abdul Kalam Technical University (AKTU), Knowledge Park 1, Greater Noida, Gautam Budh Nagar, U.P., 201310, India.
Mohammad Firoz AlamDepartment of Pharmacology & Toxicology, College of Pharmacy, Jazan University, 114, Jazan, Saudi Arabia.
Saeed AlshahraniDepartment of Pharmacology & Toxicology, College of Pharmacy, Jazan University, 114, Jazan, Saudi Arabia.
Muhanad AlhujailyDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Bisha, P.O. Box 225, Bisha, 67714, Saudi Arabia.
Mohammed Naffaa AlruwailiForensic Toxicology Services Unit, Northern Borders Region, Ministry of Health, Arar, 73241, Saudi Arabia.
Ali AssiryMohayil Hospital, Health Affairs of Aseer, Abha, 63711, Saudi Arabia.
Abdullah Saleh Salem AlrashahKing Khalid Hospital, Najran, 66251, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Depression is a pervasive neuropsychiatric disorder having significant social and economic impacts and often linked to imbalances in neurotransmitter systems. Traditional herbal medicines have garnered attention for their potential antidepressant effects, with limited research on Objectives: The present study was carried out to investigate the anti-depressant and neuromodulatory potential of hydroalcoholic extract of Methods: Depression was induced in rats by the forced swim test (FST) and tail suspension test (TST). The hydroalcoholic extract of Results: The results revealed that the Conclusions: The results suggest that

Indexed as

brain monoaminesdepressionHelianthus annuusinflammatory markersoxidative stress

Identifiers

PMID40574754
PMCPMC12198942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.