Evidence map›Paper›PMID 40574729›Full record

ReviewCancer biology & medicine2025

Multi-omics in colorectal cancer liver metastasis: applications and research advances.

Kexue Zhou, Chengxiang Yang, Yan Li

Abstract readReview
In one paragraph

Review in Cancer biology & medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Multi-omics characterization of a GPRC5AJournal of translational medicine · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. A novel role of secreted methionine adenosyltransferase α2 in colorectal liver metastases.Journal of experimental & clinical cancer research : CR · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kexue ZhouSchool of Medicine Chongqing University, Chongqing 400030, China.
Chengxiang YangSchool of Medicine Chongqing University, Chongqing 400030, China.
Yan LiSchool of Medicine Chongqing University, Chongqing 400030, China.ORCID 0000-0002-1830-2766

Funding

Natural Science Foundation of Chongqing CSTB2024NSCQ-MSX0478
6 · The paper itself

Abstract

Colorectal cancer (CRC) is a common malignant tumor with a high mortality rate worldwide. Advanced CRC often leads to liver metastasis, which has a poor prognosis, highlighting the need to investigate the underlying mechanisms. Omics, encompassing genomics, epigenomics, transcriptomics, proteomics, metabolomics, and microbiomics, enables comprehensive molecular analysis of cells and tissues. Tumor-omics research has advanced rapidly, with growing attention on CRC-related omics. However, systematic reviews on omics research specific to colorectal cancer liver metastasis (CRLM) are limited. This review summarizes the current status and progress of multi-omics research on CRLM and discusses the application of multi-omics technologies in basic research and the significant clinical implications.

Indexed as

Biomarkers, TumorColorectal NeoplasmsGenomicsLiver NeoplasmsEpigenomicsHumansMetabolomicsMultiomicsProteomicsTranscriptomeBiomarkers, TumorColorectal cancer liver metastasisepigenomicsgenomicsmetabolomicsmicrobiomicsproteomicstranscriptomics

Identifiers

PMID40574729
PMCPMC12240200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.