Evidence map›Paper›PMID 40574670›Full record

ArticleSchizophrenia bulletin2026

Temporal Relationship Between Momentary Negative Affect Intensity and Momentary Attenuated Delusions in Individuals at Clinical High-risk for Psychosis.

Ivanka Ristanovic, Danielle N Pratt, Gregory P Strauss, Vijay A Mittal

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ivanka RistanovicDepartment of Psychology, Northwestern University, Evanston, IL, United States.ORCID 0000-0003-3988-0781
Danielle N PrattDepartment of Psychology, Northwestern University, Evanston, IL, United States.ORCID 0000-0003-1581-4317
Gregory P StraussDepartment of Psychology, University of Georgia, Athens, GA, United States.
Vijay A MittalDepartment of Psychology, Northwestern University, Evanston, IL, United States.ORCID 0000-0001-9017-5119

Funding

Prodromal Inventory for Negative Symptoms (PINS): A Development and Validation StudyR01MH116039 · NIMH · UNIVERSITY OF GEORGIA · PI MITTAL, VIJAY A, STRAUSS, GREGORY P · 2019 to 2023
$3.1M
NIMH NIH HHS R01 MH116039
6 · The paper itself

Abstract

background and hypothesesResearch suggests that stress contributes to psychosis risk through an affective pathway, where heightened emotional responses to stressors lead to increased vulnerability. Specifically, individuals at clinical high-risk for psychosis (CHR-p) display more intense negative affect (NA) intensity, which is thought to exacerbate psychosis risk. The present study explored temporal dynamics between momentary NA intensity and delusional severity in CHR-p using ecological momentary assessment (EMA). Aims were to: (1) examine group differences in NA intensity and variability and (2) explore bidirectional associations between NA and attenuated delusions in the context of daily life. STUDY

designA sample of 120 CHR participants and 59 healthy controls completed 1 week of EMA surveys examining NA and attenuated delusions. Multilevel models examined time-lagged effects of NA reactivity on attenuated delusions and vice versa.

resultsConsistent with previous research, individuals at CHR displayed greater levels of NA intensity compared to healthy controls. Additionally, the CHR group exhibited variability affective changes throughout the day, suggesting a disrupted return to emotional homeostasis. Contrary to predictions, NA intensity did not predict subsequent delusional severity, highlighting potential complexities in the association that may be revealed by EMA methodologies. Instead, the study demonstrated that heightened attenuated delusional severity predicted subsequent increases in NA intensity.

conclusionsThese results demonstrated attenuated delusions exacerbate momentary elevations in NA intensity. Together with evidence from previous literature, findings underscore this relationship may be sensitive to the timescale of measurement, indicating the need for elucidating mechanisms underlying these associations to improve outcomes.

Indexed as

AffectDelusionsEcological Momentary AssessmentPsychotic DisordersAdolescentAdultFemaleHumansMaleProdromal SymptomsRiskSeverity of Illness IndexTime FactorsYoung Adultattenuated delusionsCHR-pdigital phenotypingNA intensity

Identifiers

PMID40574670
PMCPMC12996918

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.