ArticlePolymers2025
Tuning Biodegradation and Physicochemical Features of PLA/HAp Biomaterials by Incorporating Nanofibrillated Cellulose Through a Colloidal Processing Route.
Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- PLA/Collagen/Hydroxyapatite Ternary Biocomposites for Biodegradable Bone Screw Applications.Polymers · 2026Article
- Hydroxyapatite-cellulose composites: properties, fabrication methods, and applications.Journal of materials science. Materials in medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Biomaterials play a fundamental role in providing a porous structure that mimics the natural structure of human bone and serves as a support while tissue regenerates. With the use of biodegradable materials, it is possible to avoid unnecessary second surgeries for implant removal. The main objective of this article has been focused on modifying the degradation rate of a biodegradable composite material based on polylactic acid (PLA) reinforced with hydroxyapatite (HAp) by incorporating nanofibrillated cellulose (NFC), capable of tuning the porosity within the matrix. To introduce NFC into the composite material, a colloidal processing approach was chosen to improve and ensure its compatibility with the polymeric matrix. The incorporation of different ratios of NFC generally decreases the mechanical properties, but by adjusting the ratio of HAp/NFC content, this parameter is normalized. The hydrophilicity of the composite is improved by HAp/NFC incorporation, and degradation tests confirm that an increase in the percentage of NFC in the matrix is directly proportional to an increase in the degradation rates of the material. These results represent a significant improvement in personalized medicine, where the design of biodegradable biomaterials with hierarchical and controlled porosity opens new paths in the development of therapies and treatments personalized for each patient.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.