Evidence map›Paper›PMID 40574090›Full record

ArticlePharmaceutics2025

Design and Activity Evaluation of Berberine-Loaded Dual pH and Enzyme-Sensitive Colon-Targeting Microparticles.

Jingqi Sun, Xinlong Chai, Xiwen Zeng, Qingwei Wang, Yanwen Ling, Lihong Wang, Jin Su

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingqi SunDepartment of Pharmaceutics, School of Pharmacy, China Jiamusi University, Jiamusi 154007, China.ORCID 0009-0008-4674-743X
Xinlong ChaiDepartment of Pharmaceutics, School of Pharmacy, China Jiamusi University, Jiamusi 154007, China.
Xiwen ZengDepartment of Pharmaceutics, School of Pharmacy, China Jiamusi University, Jiamusi 154007, China.
Qingwei WangDepartment of Pharmaceutics, School of Pharmacy, China Jiamusi University, Jiamusi 154007, China.
Yanwen LingDepartment of Pharmaceutics, School of Pharmacy, China Jiamusi University, Jiamusi 154007, China.
Lihong WangDepartment of Pharmaceutics, School of Pharmacy, China Jiamusi University, Jiamusi 154007, China.
Jin SuDepartment of Pharmaceutics, School of Pharmacy, China Jiamusi University, Jiamusi 154007, China.

Funding

Heilongjiang Provincial Key Laboratory Fund of New Drug Development and Evaluation of the Efficacy of Toxicology kfkt2023-05Natural Science Foundation of Heilongjiang Province LH2024H003North Medicine and Functional Food Characteristic Subject Project in Heilongjiang HLJTSXK-2022-03
6 · The paper itself

Abstract

Ulcerative colitis (UC) is a multifactorial disorder, and conventional oral berberine (BBR) suffers from poor colonic targeting. This study aimed to develop a colon-targeted microparticle system (BBR-ES MPs) based on chitosan (CS) and Eudragit S-100 to enhance BBR delivery efficiency and therapeutic efficacy in UC.

Indexed as

berberinecolonic targetingintestinal floraparticlesulcerative colitis

Identifiers

PMID40574090
PMCPMC12196873

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.