Evidence map›Paper›PMID 40574039›Full record

ArticlePharmaceutics2025

In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington's Disease.

Luis C Morales, Luv Modi, Saba Abbasi Dezfouli, Amarnath Praphakar Rajendran, Remant Kc, Vaibhavi Kadam, Simonetta Sipione, Hasan Uludağ

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luis C MoralesDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0003-4194-2961
Luv ModiDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0009-0007-5173-9912
Saba Abbasi DezfouliDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0003-4960-5089
Amarnath Praphakar RajendranDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Remant KcDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0002-3554-7247
Vaibhavi KadamDepartment of Pharmacology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Simonetta SipioneDepartment of Pharmacology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Hasan UludağDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0002-1118-4170

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

gene silencingHuntington’s diseaselipopolymers

Identifiers

PMID40574039
PMCPMC12196245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.