Evidence map›Paper›PMID 40574002›Full record

ArticlePharmaceutics2025

Synthesis and Characterization of Poly(Lactic-Co-Glycolic Acid)-Paclitaxel (PLGA-PTX) Nanoparticles Evaluated in Ovarian Cancer Models.

Sylwia A Dragulska, Maxier Acosta Santiago, Sabina Swierczek, Linus Chuang, Olga Camacho-Vanegas, Sandra Catalina Camacho, Maria M Padron-Rhenals, John A Martignetti, Aneta J Mieszawska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sylwia A DragulskaDepartment of Chemistry and Biochemistry, Brooklyn College, Brooklyn, NY 11210, USA.
Maxier Acosta SantiagoDepartment of Chemistry and Biochemistry, Brooklyn College, Brooklyn, NY 11210, USA.ORCID 0000-0002-0883-331X
Sabina SwierczekRudy L. Ruggles Biomedical Research Institute, Nuvance Health, Danbury, CT 06810, USA.
Linus ChuangRudy L. Ruggles Biomedical Research Institute, Nuvance Health, Danbury, CT 06810, USA.
Olga Camacho-VanegasDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Sandra Catalina CamachoDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Maria M Padron-RhenalsDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-9108-4761
John A MartignettiRudy L. Ruggles Biomedical Research Institute, Nuvance Health, Danbury, CT 06810, USA.
Aneta J MieszawskaDepartment of Chemistry and Biochemistry, Brooklyn College, Brooklyn, NY 11210, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed a novel biodegradable poly(lactic-co-glycolic acid) (PLGA) polymer chemically modified with paclitaxel (PTX) to form a PLGA-PTX hybrid. Pre-modification of PTX enhanced its loading in PLGA-PTX nanoparticles (NPs).

Indexed as

nanoparticlesovarian cancerpaclitaxelpoly(lactic-co-glycolic acid)

Identifiers

PMID40574002
PMCPMC12196068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.