Evidence map›Paper›PMID 40573991›Full record

ArticleVaccines2025

Body Mass Index and COVID-19: An Overview Among an Italian Multicentric Cohort of Healthcare Workers in the Pre- and Post-Vaccination Eras-ORCHESTRA Project.

Gianluca Spiteri, Lorena Torroni, Maria Grazia Lourdes Monaco, Angela Carta, Francesco Taus, Alberto Modenese, Loretta Casolari, Maria Luisa Scapellato, Filippo Liviero, Francesca Larese Filon and 3 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gianluca SpiteriOccupational Medicine Unit, University Hospital of Verona, 37134 Verona, Italy.ORCID 0000-0001-8536-7095
Lorena TorroniDepartmental Faculty of Medicine, Saint Camillus International University of Health and Medical Sciences, 00131 Rome, Italy.ORCID 0000-0002-0707-7153
Maria Grazia Lourdes MonacoOccupational Medicine Unit, University Hospital of Verona, 37134 Verona, Italy.ORCID 0000-0003-4951-2528
Angela CartaOccupational Medicine Unit, University Hospital of Verona, 37134 Verona, Italy.
Francesco TausUnit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-4728-6686
Alberto ModeneseDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-0850-5615
Loretta CasolariHealth Surveillance and Workers Health promotion Service, University Hospital of Modena, 41125 Modena, Italy.
Maria Luisa ScapellatoDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padua, Italy.ORCID 0000-0003-4740-4865
Filippo LivieroDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padua, Italy.ORCID 0000-0002-4497-9287
Francesca Larese FilonUnit of Occupational Medicine, Department of Medical Science, University of Trieste, 34149 Trieste, Italy.ORCID 0000-0002-7717-0417
Francesca RuiUnit of Occupational Medicine, Department of Medical Science, University of Trieste, 34149 Trieste, Italy.ORCID 0000-0002-4788-9076
Giuseppe VerlatoUnit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.ORCID 0000-0001-5262-8818
Stefano PorruOccupational Medicine Unit, University Hospital of Verona, 37134 Verona, Italy.ORCID 0000-0003-3564-7202

Funding

Funding: The ORCHESTRA project is funded by the European Commission, Horizon 2020 Program, Grant Agreement No. 101016167. The Verona cohort was also supported by the Regional Health Authority (Azienda Zero), Veneto Region, Italy. The funding sources had n No. 101016167
6 · The paper itself

Abstract

Background The prevalence of obesity is increasing all over the world, resulting in a global health emergency. The impact of obesity on the risk of SARS-CoV-2 infection and symptom severity, especially among high-risk working populations such as health workers, deserves further studies. Methods A multicentric retrospective cohort study was conducted among health workers at four Italian University Hospitals belonging to the ORCHESTRA Project. Data were collected through an online survey, investigating sociodemographic and clinical data, until September 2022. Results The questionnaire was filled out by 5777 health workers. The median age was 46 years old (I-III quartile 20-72) and 75.5% were females. Data on BMI was available for 5470 participants. Overweight and obese subjects amounted to 23.4% and 9.8%, respectively. Naïve health workers were the majority (57.4%). Overweight and obese subjects were at a higher risk of infection only before vaccination with respect to normoweight subjects (RRR = 1.28 (IC 95% 1.01-1.62,

Indexed as

BMIobesityrisk factorsSARS-CoV-2SARS-CoV-2 vaccinationserological response

Identifiers

PMID40573991
PMCPMC12197647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.