Evidence map›Paper›PMID 40573939›Full record

ReviewVaccines2025

Vaccines and Animal Models of Nipah Virus: Current Situation and Future Prospects.

Chaoxiang Lv, Jiayue He, Qiqi Zhang, Tiecheng Wang

Abstract readReview
In one paragraph

Review in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Proteome conserved multi-epitope-based vaccine construct against Nipah virus.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Emerging microbes & infections · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chaoxiang LvThe Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.ORCID 0000-0002-0199-3169
Jiayue HeThe Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.ORCID 0000-0001-5756-6345
Qiqi ZhangThe Research Center for Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.
Tiecheng WangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China.

Funding

Sichuan Province Science and Technology Department Project 2024NSFSC0377
6 · The paper itself

Abstract

Nipah virus (NiV) is a highly pathogenic paramyxovirus characterized by zoonotic infection, high mortality, and a lack of effective treatment, posing a serious threat to global public health security. Currently, it still lacks specific treatments or approved vaccines, and is listed as a potential pandemic threat pathogen by the World Health Organization. This paper systematically reviews the core progress and challenges of NiV investigation, with a focus on the development of animal models, vaccine development strategies, treatment strategy, and bottlenecks in translational medicine. Additionally, we discuss the strengths and limitations of existing animal models, including ferrets, hamsters, mice, and non-human primates (NHPs), and assess advances in vaccine platforms such as viral vectors, subunit vaccines, and mRNA-based vaccine candidates. The paper critically reviews the challenges facing translational research, conservation correlates, and outbreak preparedness, while also providing future research directions for pandemic preparedness and public health security strategies.

Indexed as

animal modelsNiVpandemic preparednessvaccine developmentzoonosis

Identifiers

PMID40573939
PMCPMC12197635

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.