Evidence map›Paper›PMID 40573930›Full record

ArticleVaccines2025

A Cross-Sectional Study to Understand HPV Vaccine Hesitancy and Influencing Factors in Italian Adults.

Marianna Riccio, Azzurra Massimi, Erika Renzi, Michele Innocenzio, Roberta Siliquini, Fabrizio Bert, Anna Odone, Carolina Marzuillo, Paolo Villari, Corrado De Vito

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marianna RiccioDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0009-0001-4699-4800
Azzurra MassimiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.
Erika RenziDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-9760-0245
Michele InnocenzioDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-7647-7193
Roberta SiliquiniDepartment of Public Health and Paediatric Sciences, University of Turin, 10126 Turin, Italy.
Fabrizio BertDepartment of Public Health and Paediatric Sciences, University of Turin, 10126 Turin, Italy.
Anna OdoneDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-5657-9774
Carolina MarzuilloDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-7299-5727
Paolo VillariDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.
Corrado De VitoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Funding

Ministero dell'Università e della Ricerca (Italy), Piano Nazionale di Ripresa e Resilienza, and EU. Project number PE00000007
6 · The paper itself

Abstract

objectivesThe Human papillomavirus (HPV) vaccine is a cornerstone of cancer prevention, yet uptake remains suboptimal in many countries. This study analyzed the factors influencing HPV vaccine acceptance among adults, including a focused analysis of parental behaviors.

methodsData were collected through a web-based survey using a questionnaire. We performed univariable analysis and three logistic regression analyses to investigate the determinants in the overall sample and among parents.

resultsA total of 1821 participants were surveyed. HPV vaccination uptake was low, with only 6.9% of the total sample and 7.6% of young adults (18-35 yo) vaccinated. Among parents, 47.9% had vaccinated children aged 12-17, and 21.1% those aged 18 and over. Higher health literacy was associated with positive attitudes (OR 2.03, 95% CI 1.48-2.79), while receiving information from pediatricians or gynecologists was linked to children's vaccination status (OR 7.30, 95% CI 2.29-23.31) and parents' intentions for future HPV vaccination (OR 5.86, 95% CI 1.85-18.50). Adequate knowledge emerged as a strong predictor of positive attitudes (OR 6.50, 95% CI 4.91-8.61) and parents' intentions (OR 4.89, 95% CI 2.21-10.84). Vaccination status was a key factor influencing parental decisions and overall vaccine acceptance.

conclusionsThese findings highlight the critical role of health professionals and the need for targeted communication to address persistent knowledge gaps and promote HPV vaccine confidence within general population.

Indexed as

human papillomavirusItalysurveyvaccine hesitancy

Identifiers

PMID40573930
PMCPMC12197334

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.