Evidence map›Paper›PMID 40573835›Full record

ReviewPlants (Basel, Switzerland)2025

Biosynthesis and Regulatory Mechanisms of Plant Flavonoids: A Review.

Yuye Mao, Jiajia Luo, Zeping Cai

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Overexpression ofBiology · 2026
    Article
  7. PlantInternational journal of molecular sciences · 2026
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Genome-Wide Identification ofPlants (Basel, Switzerland) · 2026
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuye MaoSchool of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China.
Jiajia LuoSchool of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China.
Zeping CaiSchool of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China.ORCID 0000-0002-2097-0077

Funding

College Student Innovation and Entrepreneurship Training Program Project 202410589092National Natural Science Foundation of China 32460348
6 · The paper itself

Abstract

Flavonoids are a class of secondary metabolites synthesized by plants, characterized by a C6-C3-C6 carbon skeleton and derived from the phenylpropane metabolism pathway. They play crucial biological roles, not only in plant pigment production and responses to biotic and abiotic stresses but also in medicinal applications. Consequently, the biosynthesis and regulatory mechanisms of flavonoids have been a focal point in plant transcription and gene expression research. The biosynthetic pathways of flavonoids include branches such as isoflavones, flavones, flavonols, anthocyanins, and proanthocyanidins, with some pathways and key enzymes already well-characterized. Studies indicate that plant flavonoids are regulated by various factors, including transcription factors, non-coding endogenous small RNAs (miRNAs), and plant hormones. This review systematically summarizes the structure and classification of plant flavonoids, their biosynthetic and regulatory mechanisms, and the factors influencing flavonoid synthesis. By discussing the regulation of flavonoid-related gene expression in plants, this work provides valuable insights and a theoretical foundation for future research and applications of flavonoids.

Indexed as

biosynthesisflavonoidsgene expressionregulationtranscription factors

Identifiers

PMID40573835
PMCPMC12196789

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.