Evidence map›Paper›PMID 40573726›Full record

ReviewPlants (Basel, Switzerland)2025

Role of Serotonin in Cadmium Mitigation in Plants.

Hesham F Oraby, Nehal Z Elnaggar, Ahmad A Omar, Azza H Mohamed

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hesham F OrabyDepartment of Crop Science, Faculty of Agriculture, Zagazig University, Zagazig 44519, Egypt.ORCID 0000-0003-4675-3297
Nehal Z ElnaggarDepartment of Crop Science, Faculty of Agriculture, Zagazig University, Zagazig 44519, Egypt.
Ahmad A OmarBiochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0003-3198-624X
Azza H MohamedCitrus Research and Education Center, University of Florida (IFAS), Lake Alfred, FL 33850, USA.ORCID 0000-0002-4162-8932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contamination of the soil with cadmium (Cd) presents serious hazards to plant growth, ecosystem harmony, and human health. Plants have evolved various mechanisms to address Cd toxicity, such as sequestration, chelation, and antioxidant defense systems. Knowledge of these mechanisms is an important requisite for the development of strategies to relieve Cd stress in plants. More recent studies also implicate the role of the neurotransmitter 5-hydroxytryptamine (serotonin) in enabling Cd mitigation behavior in plants. Beyond its well-known role in animals, serotonin has emerged as a vital signaling molecule in plants, contributing to stress responses and regulatory pathways. This review focuses on the different Cd tolerance mechanisms in plants and describes the role of serotonin in protection against Cd toxicity. Moreover, it investigates how serotonin interacts with other signaling molecules to coordinate Cd stress responses. Understanding the intricate network of Cd tolerance mechanisms and the involvement of serotonin is essential for developing effective strategies to combat Cd stress in plants and improve environmental quality.

Indexed as

cadmium toxicityreactive oxygen speciesserotoninstress responsetolerance mechanisms

Identifiers

PMID40573726
PMCPMC12196318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.