Evidence map›Paper›PMID 40573434›Full record

ArticleViruses2025

Prevalence of Hepatitis C in the Emilia-Romagna Region of Italy: Population-Wide Screening.

Gianmarco Imperiali, Matteo Fiore, Alessandro Bianconi, Giovanna Mattei, Giulio Matteo, Giuseppe Diegoli, Esther Rita De Gioia, Cecilia Acuti Martellucci, Maria Elena Flacco, Lamberto Manzoli and 1 more

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gianmarco ImperialiSection of Hygiene and Preventive Medicine, University of Bologna, 40126 Bologna, Italy.
Matteo FioreSection of Hygiene and Preventive Medicine, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-6868-2130
Alessandro BianconiSection of Hygiene and Preventive Medicine, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-4962-7520
Giovanna MatteiEmilia-Romagna Region Collective Prevention and Public Health Department, 40127 Bologna, Italy.
Giulio MatteoEmilia-Romagna Region Collective Prevention and Public Health Department, 40127 Bologna, Italy.
Giuseppe DiegoliEmilia-Romagna Region Collective Prevention and Public Health Department, 40127 Bologna, Italy.
Esther Rita De GioiaSection of Hygiene and Preventive Medicine, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-3764-2280
Cecilia Acuti MartellucciSection of Hygiene and Preventive Medicine, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-4308-2144
Maria Elena FlaccoDepartment of Environmental and Prevention Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-1404-4314
Lamberto ManzoliSection of Hygiene and Preventive Medicine, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-8129-9344
Regional Hcv Working Group

Funding

Italian Ministers of Health and Economy Gazzetta Ufficiale Serie Generale n.162, 08-07-2021 (21A04075)
6 · The paper itself

Abstract

In agreement with WHO recommendations, the Emilia-Romagna Region, Italy, implemented a population-wide HCV screening program for the treatment of the large asymptomatic infected population. From January 2022, the free-of-charge screening targeted all residents born between 1969 and 1989, prison inmates, and injection drug users. Participants were recruited using phone messages, electronic health record notifications, public advertisement, and direct contact with general practitioners. A single blood sample was collected for anti-HCV IgG testing and, if positive, for reflex HCV-RNA testing. Infected subjects were offered an evidence-based therapeutic pathway. By June 2024, 72.8% of high-risk subjects (

Indexed as

Hepatitis CMass ScreeningAdultAgedFemaleHepacivirusHepatitis C AntibodiesHumansItalyMaleMiddle AgedPrevalenceRNA, ViralYoung AdultHepatitis C AntibodiesRNA, Viral1969–1989drug addictionHCV prevalenceHepatitis C VirusItalyprison inmatesscreening

Identifiers

PMID40573434
PMCPMC12197420

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.