Evidence map›Paper›PMID 40573424›Full record

ArticleViruses2025

Changes in Saliva Analytes in Pigs in Different Clinical Situations from Farms Positive to Porcine Reproductive and Respiratory Syndrome (PRRS): A Pilot Study.

Eva Llamas-Amor, Silvia Martínez-Subiela, Fernando Tecles, Aida Miralles, Elena Goyena, Andrea Martínez-Martínez, José Joaquín Cerón, Alberto Muñoz-Prieto

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eva Llamas-AmorInterdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain.ORCID 0009-0000-3070-9342
Silvia Martínez-SubielaInterdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain.ORCID 0000-0002-1524-1558
Fernando TeclesInterdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain.
Aida MirallesDepartment of Anatomy and Comparative Pathological Anatomy, Faculty of Veterinary Medicine, University of Murcia, 30100 Murcia, Spain.ORCID 0009-0004-8941-4601
Elena GoyenaDepartment of Anatomy and Comparative Pathological Anatomy, Faculty of Veterinary Medicine, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0001-8993-2792
Andrea Martínez-MartínezAgropecuaria Casas Nuevas Ltd., 30320 Murcia, Spain.ORCID 0009-0009-4057-0730
José Joaquín CerónInterdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain.
Alberto Muñoz-PrietoInterdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain.ORCID 0000-0001-6865-8712

Funding

Fundación Séneca - Agencia de Ciencia y Tecnología de la Región de Murcia 21916/PI/22Fundación Séneca - Agencia de Ciencia y Tecnología de la Región de Murcia 22296/FPI/23Ministerio de Ciencia e Innovación, Agencia Estatal de Investigación (AEI), Spain, and The Euro-pean Next Generation Funds (NextgenerationEU) RYC2021-033660-I
6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome (PRRS) is aworldwide spread disease. This study analyzed the changes in saliva analytes of pigs infected with PRRS virus (PRRSV) in different clinical conditions that can appear in PRRSV-positive farms. Biomarkers for inflammation (haptoglobin, total proteins), immune response (adenosine deaminase), tissue damage (lactate dehydrogenase), stress (alpha-amylase), and sepsis (calprotectin, aldolase, Serpin B12) were measured in pigs under three clinical scenarios: (1) no evident clinical signs, (2) clinical signs indicating PRRSV activation, and (3) secondary bacterial infection by

Indexed as

Porcine Reproductive and Respiratory SyndromeSalivaAnimalsBiomarkersFarmsPilot ProjectsPorcine respiratory and reproductive syndrome virusSwineBiomarkersbiomarkerspigPRRSVsaliva

Identifiers

PMID40573424
PMCPMC12197551

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.