Neonatal Meningitis Due to Herpes Simplex Virus Type 1 and Enterovirus Coinfection: Case Report and Review of the Literature.

Carolina Coramusi, Alessandra Rizzoli, Caterina Alegiani, Susanna Bonafoni, Cinzia Auriti, Pasquale Parisi, Maria Eleonora Scapillati

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In one paragraph

Review in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolina CoramusiFaculty of Medicine and Psychology, Sapienza University, 00185 Rome, Italy.ORCID 0009-0005-7454-9199

Alessandra RizzoliSan Pietro Fatebenefratelli Hospital, Neonatal Intensive Care Unit, Sapienza University, 86100 Rome, Italy.

Caterina AlegianiSan Pietro Fatebenefratelli Hospital, Neonatal Intensive Care Unit, Sapienza University, 86100 Rome, Italy.

Susanna BonafoniSan Pietro Fatebenefratelli Hospital, Neonatal Intensive Care Unit, Sapienza University, 86100 Rome, Italy.

Cinzia AuritiDepartmental Faculty of Medicine, Saint Camillus International University, 00131 Rome, Italy.ORCID 0000-0001-9820-6557

Pasquale ParisiNESMOS Department, Faculty of Medicine & Psychology, Sapienza University, c/o Sant' Andrea Hospital, 00185 Rome, Italy.ORCID 0000-0001-9042-8120

Maria Eleonora ScapillatiSan Pietro Fatebenefratelli Hospital, Neonatal Intensive Care Unit, Sapienza University, 86100 Rome, Italy.ORCID 0009-0009-4675-6405

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the first 90 days, most meningitis cases are viral. Newborns often show nonspecific symptoms, making early diagnosis difficult but crucial for effective treatment and good outcomes. Cerebro-spinal fluid (CSF) analysis is the gold standard for diagnosis, enabling targeted therapy. We report on a newborn with rare viral meningitis due to herpes simplex virus type 1 and enterovirus coinfection. This uncommon situation complicates diagnostic and therapeutic management. We share our experience and review the limited literature on such neonatal viral coinfections.

Indexed as

CoinfectionEnterovirusEnterovirus InfectionsHerpes SimplexHerpesvirus 1, HumanMeningitis, ViralAntiviral AgentsHumansInfant, NewbornAntiviral Agentscase reportcoinfectionenterovirusHSVneonatal meningitisnewborn

Identifiers

PMID40573380

DOI10.3390/v17060790

PMCPMC12197516

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.