Evidence map›Paper›PMID 40573315›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Neuroprotective Effect of Methylene Blue in a Rat Model of Traumatic Optic Neuropathy.

Nicolás S Ciranna, Ronan Nakamura, Rafael Peláez, Álvaro Pérez-Sala, Patricia Sarrión, Juan C Fernández, Alejandra Paganelli, Agustín P Aranalde, Ulises P Ruiz, Juan J López-Costa and 3 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nicolás S CirannaInstitute of Cell Biology and Neurosciences "Prof. E. de Robertis", Faculty of Medicine, University of Buenos Aires, Buenos Aires 1821, Argentina.
Ronan NakamuraInstitute of Cell Biology and Neurosciences "Prof. E. de Robertis", Faculty of Medicine, University of Buenos Aires, Buenos Aires 1821, Argentina.ORCID 0000-0002-0816-0020
Rafael PeláezBiomarkers and Molecular Signaling Group, Neurodegenerative Diseases Area, Center for Biomedical Research of La Rioja (CIBIR), 26006 Logroño, Spain.ORCID 0000-0002-4047-6017
Álvaro Pérez-SalaBiomarkers and Molecular Signaling Group, Neurodegenerative Diseases Area, Center for Biomedical Research of La Rioja (CIBIR), 26006 Logroño, Spain.ORCID 0000-0002-7310-6792
Patricia SarriónBiomarkers and Molecular Signaling Group, Neurodegenerative Diseases Area, Center for Biomedical Research of La Rioja (CIBIR), 26006 Logroño, Spain.
Juan C FernándezInstitute of Cell Biology and Neurosciences "Prof. E. de Robertis", Faculty of Medicine, University of Buenos Aires, Buenos Aires 1821, Argentina.
Alejandra PaganelliInstitute of Cell Biology and Neurosciences "Prof. E. de Robertis", Faculty of Medicine, University of Buenos Aires, Buenos Aires 1821, Argentina.
Agustín P AranaldeInstitute of Cell Biology and Neurosciences "Prof. E. de Robertis", Faculty of Medicine, University of Buenos Aires, Buenos Aires 1821, Argentina.
Ulises P RuizInstitute of Cell Biology and Neurosciences "Prof. E. de Robertis", Faculty of Medicine, University of Buenos Aires, Buenos Aires 1821, Argentina.
Juan J López-CostaInstitute of Cell Biology and Neurosciences "Prof. E. de Robertis", Faculty of Medicine, University of Buenos Aires, Buenos Aires 1821, Argentina.ORCID 0000-0001-5802-1726
César F LoidlInstitute of Cell Biology and Neurosciences "Prof. E. de Robertis", Faculty of Medicine, University of Buenos Aires, Buenos Aires 1821, Argentina.
Alfredo MartínezAngiogenesis Group, Oncology Area, Center for Biomedical Research of La Rioja (CIBIR), 26006 Logroño, Spain.ORCID 0000-0003-4882-4044
Manuel Rey-FunesInstitute of Cell Biology and Neurosciences "Prof. E. de Robertis", Faculty of Medicine, University of Buenos Aires, Buenos Aires 1821, Argentina.

Funding

Fundación Rioja Salud ONCO1University of Buenos Aires 20020190100284BAUniversity of Buenos Aires 20020220100061BA
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

electroretinographymethylene blueneurodegenerationneuroprotectionoptic neuropathyretinal ganglion cellstrauma

Identifiers

PMID40573315
PMCPMC12196352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.