Evidence map›Paper›PMID 40573221›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Antimicrobial Smart Dressings for Combating Antibiotic Resistance in Wound Care.

Alina-Georgiana Cristea Hohotă, Elena-Lăcrămioara Lisă, Simona Iacob Ciobotaru, Ionut Dragostin, Claudia Simona Ștefan, Iuliu Fulga, Andra Monica Anghel Ștefan, Maria Dragan, Ionela Daniela Morariu, Oana-Maria Dragostin

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. EvaluatingParasite epidemiology and control · 2026
    Article
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  5. Review
  6. Article
  7. Proangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract ofInternational journal of molecular sciences · 2026
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alina-Georgiana Cristea HohotăResearch Centre in the Medical-Pharmaceutical Field, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800201 Galati, Romania.ORCID 0000-0001-9985-5057
Elena-Lăcrămioara LisăResearch Centre in the Medical-Pharmaceutical Field, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800201 Galati, Romania.ORCID 0000-0001-9310-9731
Simona Iacob CiobotaruResearch Centre in the Medical-Pharmaceutical Field, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800201 Galati, Romania.
Ionut DragostinResearch Centre in the Medical-Pharmaceutical Field, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800201 Galati, Romania.
Claudia Simona ȘtefanResearch Centre in the Medical-Pharmaceutical Field, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800201 Galati, Romania.
Iuliu FulgaResearch Centre in the Medical-Pharmaceutical Field, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800201 Galati, Romania.
Andra Monica Anghel ȘtefanResearch Centre in the Medical-Pharmaceutical Field, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800201 Galati, Romania.
Maria DraganDepartment of Pharmaceutical Sciences II, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Ionela Daniela MorariuDepartment of Environmental and Food Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-7083-8197
Oana-Maria DragostinResearch Centre in the Medical-Pharmaceutical Field, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800201 Galati, Romania.

Funding

"Dunărea de Jos University of Galați" 7957/31.03.2025
6 · The paper itself

Abstract

Wound healing is a complex, tightly regulated process essential for maintaining skin barrier function. Chronic wounds, often complicated by biofilm-forming bacteria and elevated oxidative stress, pose significant challenges in clinical management. The rise of antibiotic-resistant bacteria has further exacerbated the problem, limiting therapeutic options and complicating wound treatment. Traditional wound care approaches frequently fail to provide real-time accurate insights into wound status, leading to delayed or suboptimal treatments. Recent advancements in modern and smart wound dressings, which integrate various biosensors, different new drug delivery systems, and wireless communication technology, offers promising solutions for monitoring wound progression over time. These innovations enable early detection of adverse events such as bacterial infections and inflammation, facilitating more effective, on-demand treatment. This review highlights the current state of antibiotic-embedded wound dressings, discusses their limitations, and explores the potential of next-generation wound dressings incorporating microelectronic sensors for real-time monitoring and adaptive therapeutic responses to support healing and combat antimicrobial resistance.

Indexed as

antimicrobial resistanceantimicrobialswound dressingswound infection

Identifiers

PMID40573221
PMCPMC12196261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.