ArticlePharmaceuticals (Basel, Switzerland)2025
Michael Acceptor Compounds as Hemoglobin Oxygen Affinity Modulators for Reversing Sickling of Red Blood Cells.
Khadijah A Mohammad, Asala H Naghi, Mohini S Ghatge, Benita Balogun, Mariana Macias, Salma Roland, Albert Opare, Osheiza Abdulmalik, Martin K Safo, Abdelsattar M Omar and 1 more
Abstract read
In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Khadijah A MohammadDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Asala H NaghiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Mohini S GhatgeDepartment of Medicinal Chemistry, School of Pharmacy and Center for Drug Discovery, Virginia Commonwealth University, Richmond, VA 23219, USA.
Benita BalogunDivision of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Mariana MaciasDivision of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Salma RolandDivision of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Albert OpareDepartment of Medicinal Chemistry, School of Pharmacy and Center for Drug Discovery, Virginia Commonwealth University, Richmond, VA 23219, USA.
Osheiza AbdulmalikDivision of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0003-2497-4291 Martin K SafoDepartment of Medicinal Chemistry, School of Pharmacy and Center for Drug Discovery, Virginia Commonwealth University, Richmond, VA 23219, USA.ORCID 0000-0002-9536-1743 Abdelsattar M OmarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-9825-3465 Moustafa E El-ArabyDepartment of Medicinal Chemistry, School of Pharmacy and Center for Drug Discovery, Virginia Commonwealth University, Richmond, VA 23219, USA.ORCID 0000-0002-7932-2226 Funding
Hemoglobin Modifiers for Sickle Cell Disease TherapyR01MD009124 · NIMHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI SAFO, MARTIN K · 2014 to 2018
$2.1MTargeted Identification of Dual Acting Antisickling Agents for Sickle Cell Disease TherapyR61HL156158 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI ABDULMALIK, OSHEIZA Y, SAFO, MARTIN K · 2021 to 2022
$1.1MTargeted Identification of Dual Acting Antisickling Agents for Sickle Cell Disease TherapyR33HL156158 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI ABDULMALIK, OSHEIZA Y, SAFO, MARTIN K · 2023 to 2023
$572kDeanship of Scientific Research (DSR) at King Abdulaziz University, Jeddah IFPIP-384-166-1443NHLBI NIH HHS R33 HL156158NHLBI NIH HHS R61 HL156158NIMHD NIH HHS R01 MD009124
6 · The paper itselfAbstract
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Indexed as
antisicklingHb oxygen affinityhemoglobinMichael acceptorpolymerizationsickle cell disease
Identifiers
PMID40573180
PMCPMC12196294
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