Evidence map›Paper›PMID 40573151›Full record

SynthesisNutrients2025

Beyond Folate: The Emerging Role of Maternal Vitamin B12 in Neural Tube Development.

Lirong Nie, Xinru Liu, Xiaoxue Li, Ziyang Ren, Xiao Cheng, Yuwei Wu, Zhiwen Li, Jufen Liu

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Vitamin BThe Cochrane database of systematic reviews · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lirong NieInstitute of Reproductive and Child Health, National Health Commission Key Laboratory of Reproductive Health, Peking University, No 38 College Rd, Haidian District, Beijing 100191, China.
Xinru LiuSchool of Public Health, Peking University, No 38 College Rd, Haidian District, Beijing 100191, China.
Xiaoxue LiDepartment of Health Education, Cangzhou City Center for Disease Prevention and Control, Cangzhou 061000, China.
Ziyang RenInstitute of Reproductive and Child Health, National Health Commission Key Laboratory of Reproductive Health, Peking University, No 38 College Rd, Haidian District, Beijing 100191, China.
Xiao ChengInstitute of Reproductive and Child Health, National Health Commission Key Laboratory of Reproductive Health, Peking University, No 38 College Rd, Haidian District, Beijing 100191, China.ORCID 0009-0000-5511-1961
Yuwei WuInstitute of Reproductive and Child Health, National Health Commission Key Laboratory of Reproductive Health, Peking University, No 38 College Rd, Haidian District, Beijing 100191, China.
Zhiwen LiInstitute of Reproductive and Child Health, National Health Commission Key Laboratory of Reproductive Health, Peking University, No 38 College Rd, Haidian District, Beijing 100191, China.ORCID 0000-0001-7570-3809
Jufen LiuInstitute of Reproductive and Child Health, National Health Commission Key Laboratory of Reproductive Health, Peking University, No 38 College Rd, Haidian District, Beijing 100191, China.ORCID 0000-0001-5844-8973

Funding

Key Project of the Regional Innovation and Development Joint Fund of the National Natural Science Foundation of China U23A20420
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Folic AcidNeural TubeNeural Tube DefectsVitamin B 12Dietary SupplementsFemaleHumansMaternal Nutritional Physiological PhenomenaPregnancyVitamin B 12 DeficiencyFolic AcidVitamin B 12folic acidmeta-analysisneural tube defectsvitamin B12

Identifiers

PMID40573151
PMCPMC12196037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.