Evidence map›Paper›PMID 40573070›Full record

ReviewNutrients2025

Nutritional Management for Preterm Infants with Common Comorbidities: A Narrative Review.

Cheng-Yen Chen, Mei-Yin Lai, Cheng-Han Lee, Ming-Chou Chiang

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Prevention and management of metabolic bone disease of prematurity: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Metabolomics in neonatal sepsis: A critical appraisal of current evidence.Computational and structural biotechnology journal · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cheng-Yen ChenDivision of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan 33305, Taiwan.
Mei-Yin LaiDivision of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan 33305, Taiwan.ORCID 0009-0004-6525-9352
Cheng-Han LeeDivision of Neonatology, Department of Pediatrics, Changhua Christian Children's Hospital, Changhua 50006, Taiwan.ORCID 0000-0003-3283-2007
Ming-Chou ChiangDivision of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan 33305, Taiwan.ORCID 0000-0003-1109-0665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complications observed in preterm infants are largely attributable to underdeveloped organ systems and inadequate nutritional stores at birth. Insufficient nutritional support can further exacerbate persistent sequelae, such as bronchopulmonary dysplasia (BPD), metabolic bone disease of prematurity (MBDP), and retinopathy of prematurity (ROP). As a result, clinicians have collaborated to develop optimal nutrition strategies for preterm neonates. However, these clinical nutrition plans may be hindered by several factors, including fluid restrictions due to patent ductus arteriosus (PDA) and delayed enteral nutrition following necrotizing enterocolitis (NEC). Modified strategies for specific conditions can help prevent further deterioration, but inadequate nutritional support may limit organ growth and contribute to additional complications. Achieving an optimal balance between nutritional support and managing specific medical conditions varies across institutions. In addition to fluid balance and energy intake, supplementary nutrition-such as vitamins and probiotics-plays a crucial role in disease prevention. Drawing on recent evidence and our clinical experiences with neonatal nutritional strategies, this review article summarizes the specialized nutritional management required for preterm neonates with conditions such as BPD, NEC, MBDP, PDA, and ROP.

Indexed as

Infant Nutritional Physiological PhenomenaInfant, PrematureInfant, Premature, DiseasesNutritional SupportBone Diseases, MetabolicBronchopulmonary DysplasiaComorbidityDuctus Arteriosus, PatentEnteral NutritionEnterocolitis, NecrotizingHumansInfant, NewbornRetinopathy of Prematurityenteral nutritionextremely low birth weight infantmorbiditiesnutritionparenteral nutritionpreterm neonatesvery low birth weight infant

Identifiers

PMID40573070
PMCPMC12195945

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.