ReviewMaterials (Basel, Switzerland)2025
Decellularized Extracellular Matrices for Skin Wound Treatment.
Review in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Hydrogels in the Management of Peripheral Venous Disease: Bridging Material Design and Clinical Evidence.Gels (Basel, Switzerland) · 2026Review
- ADM-Assisted Breast Reconstruction vs Micro-Polyurethane Foam-Covered Implants in the Prepectoral Space: A Monocentric Study.Aesthetic plastic surgery · 2026Article
- Benchmarking of Decellularization Protocols for Small Intestinal Submucosa: Defining the Gold Standard for Functional Tissue Engineering.Materials (Basel, Switzerland) · 2026Article
- The Promise of 3D Biomaterial Bioprinting for Wound-Healing and Skin Tissue Restoration.Life (Basel, Switzerland) · 2026Review
- Autologous Extracellular Matrix-Based Cell-Free Therapy for Tissue Regeneration Through Trem2Exploration (Beijing, China) · 2026Article
- The Use of Extracellular Matrix in the Complex Reconstruction of the Lower Leg After Massive Avulsion.Plastic and reconstructive surgery. Global open · 2026Article
- MSC Origin and Biomechanical Conditioning Determine ECM Maturation in Tissue-Engineered Matrix.Biomedicines · 2026Article
- Advances in Decellularization of Fish Wastes for Extracellular Matrix Extraction in Sustainable Tissue Engineering and Regenerative Medicine.Bioengineering (Basel, Switzerland) · 2026Review
- Immunomodulatory role of decellularized extracellular matrix in skin wound healing.Materials today. Bio · 2026Review
- Multifunctional Skin Dermal Extracellular Matrix Enabling Skin-Relevant Bioactivity for Tissue Remodeling, Hydration, and Anti-Hyperpigmentation.Journal of microbiology and biotechnology · 2026Article
- Smart Healing for Wound Repair: Emerging Multifunctional Strategies in Personalized Regenerative Medicine and Their Relevance to Orthopedics.Antibiotics (Basel, Switzerland) · 2026Review
- Bioactive Hydrogel Dressings Incorporating Decellularized Ovine Liver Extracellular Matrix (ECM) for Effective Wound Regeneration.BioMed research international · 2026Article
- A caffeic acid-loaded hydrogel attenuates inflammation and accelerates infected wound healing.Frontiers in bioengineering and biotechnology · 2026Article
- Porcine decellularized splenic matrix hydrogel-based vesicle sustained-release System: A dual-regulatory biomaterial for accelerated wound healing via angiogenesis and immune remodeling.Materials today. Bio · 2025Article
- Smart Hydrogels in Wearable Electronics for Wound Treatments.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Utilization of a Multi-Tissue Extracellular Matrix in Complex Wound Care in Gaza: A Case Series.Antibiotics (Basel, Switzerland) · 2025Article
- Inflammation-Responsive Hydrogels in Perioperative Pain and Wound Management: Design Strategies and Emerging Potential.Gels (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Skin trauma, especially chronic trauma, poses a significant clinical challenge, often leading to severe disability or even death. Traditional treatment methods exhibit several limitations in terms of efficacy, material availability, and biocompatibility. The development of decellularized extracellular matrices (dECMs) has led to revolutionary progress in this field. These materials retain the bioactive components of the natural extracellular matrix (ECM) and, combined with their excellent physical structure, promote wound healing. Preclinical studies have demonstrated that dECM-based dressings can enhance the re-epithelialization rate by 20-50% and shorten the healing cycle of chronic wounds by 40%. This article systematically reviews the application of dECM in wound repair. First, it outlines the pathophysiology of wound healing, focusing on the mechanisms by which key ECM components promote wound healing. Next, it classifies decellularized materials and proposes material design schemes for different types of damage. Finally, the limitations of current dECM-based wound treatments and future research directions are discussed. This review aims to provide a theoretical framework and technical reference for researchers in related fields, promoting the widespread application of dECM materials for skin trauma treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.