Evidence map›Paper›PMID 40572822›Full record

ArticleMaterials (Basel, Switzerland)2025

Biomaterials Based on Bee Products and Their Effectiveness in Soft Tissue Regeneration.

Corina Dana Dumitru, Ionela Andreea Neacșu, Ovidiu Cristian Oprea, Ludmila Motelica, Bianca Voicu Balasea, Cornelia-Ioana Ilie, Florica Marinescu, Alexandra Ripszky, Silviu-Mirel Pituru, Ecaterina Andronescu

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Microorganisms · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Corina Dana DumitruDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 1-7 Gheorghe Polizu, 011061 Bucharest, Romania.
Ionela Andreea NeacșuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 1-7 Gheorghe Polizu, 011061 Bucharest, Romania.ORCID 0000-0003-3197-6455
Ovidiu Cristian OpreaNational Research Center for Micro and Nanomaterials, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei, 060042 Bucharest, Romania.ORCID 0000-0002-8145-1094
Ludmila MotelicaNational Research Center for Micro and Nanomaterials, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei, 060042 Bucharest, Romania.ORCID 0000-0002-3371-4136
Bianca Voicu BalaseaInterdisciplinary Center for Dental Research and Development, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Str., 020956 Bucharest, Romania.ORCID 0009-0002-7073-3309
Cornelia-Ioana IlieDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 1-7 Gheorghe Polizu, 011061 Bucharest, Romania.ORCID 0000-0002-5504-5156
Florica MarinescuDepartment of Botany and Microbiology, Faculty of Biology, University of Bucharest, 1-3 Aleea Portocalelor Str., 060101 Bucharest, Romania.
Alexandra RipszkyInterdisciplinary Center for Dental Research and Development, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Str., 020956 Bucharest, Romania.ORCID 0000-0002-4345-282X
Silviu-Mirel PituruInterdisciplinary Center for Dental Research and Development, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Str., 020956 Bucharest, Romania.
Ecaterina AndronescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 1-7 Gheorghe Polizu, 011061 Bucharest, Romania.ORCID 0000-0002-2226-5849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing prevalence of antibiotic-resistant bacteria has stimulated the search for alternative antimicrobial agents with greater efficacy, low toxicity, and minimal resistance potential. Natural products, such as honey, propolis, and royal jelly, have shown promise due to their biological properties. The integration of natural products like honey and propolis in biomaterials represents a synergistic approach to combat the growing threat of resistant bacterial infections while improving wound care and soft tissue engineering applications. In the present work, we obtained sodium alginate films based on honey, propolis, royal jelly, and their mixture coated with chitosan for soft tissue regeneration. SEM showed that adding bee products altered surface morphology, affecting roughness, porosity, and microstructure. Spectral analysis confirmed specific chemical bonds, while thermal studies indicated a good stability up to 115 °C. The antimicrobial activity was evaluated against Gram-positive (

Indexed as

alginatebiomaterialschitosannatural/bee productswound healing

Identifiers

PMID40572822
PMCPMC12193722

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.