Evidence map›Paper›PMID 40572573›Full record

ArticleMolecules (Basel, Switzerland)2025

Discovery of Novel Inhibitors of

Kaige Li, Wei Xia, John Z H Zhang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kaige LiShanghai Engineering Research Center of Molecular Therapeutics and New Drug, Development, Shanghai Key Laboratory of Green Chemistry & Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.ORCID 0009-0007-2426-0105
Wei XiaNYU-ECNU Center for Computational Chemistry and Shanghai Frontiers Science Center of AI and DL, New York University Shanghai, Shanghai 200126, China.
John Z H ZhangShanghai Engineering Research Center of Molecular Therapeutics and New Drug, Development, Shanghai Key Laboratory of Green Chemistry & Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.ORCID 0000-0003-4612-1863

Funding

National Natural Science Foundation of China 22333006, 92270001
6 · The paper itself

Abstract

To address the surge in

Indexed as

Antifungal AgentsAspergillus fumigatusEnzyme InhibitorsOxidoreductases Acting on CH-CH Group DonorsDihydroorotate DehydrogenaseDrug DiscoveryDrug Evaluation, PreclinicalMicrobial Sensitivity TestsMolecular Docking SimulationMolecular Dynamics SimulationStructure-Activity RelationshipAntifungal AgentsDihydroorotate DehydrogenaseEnzyme InhibitorsOxidoreductases Acting on CH-CH Group DonorsAfDHODHbinding free energycomputer-aided drug designsmall molecule inhibitorsvirtual screening

Identifiers

PMID40572573
PMCPMC12196321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.