Evidence map›Paper›PMID 40572566›Full record

ArticleMolecules (Basel, Switzerland)2025

Rapid Detection of Chlorpheniramine Maleate in Human Blood and Urine Samples Based on NiCoP/PVP/PAN/CNFs Electrochemiluminescence Sensor.

Yi Zhang, Jiayu Zhao, Jiaxing Chen, Tingfan Tang, Hao Cheng

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi ZhangSchool of Biology, Food and Environment, Hefei University, Hefei 230601, China.ORCID 0000-0001-9229-3813
Jiayu ZhaoGuangxi Key Laboratory of Green Processing of Sugar Resources, Guangxi Liuzhou Luosifen Research Center of Engineering Technology, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545006, China.
Jiaxing ChenSchool of Biology, Food and Environment, Hefei University, Hefei 230601, China.
Tingfan TangGuangxi Key Laboratory of Green Processing of Sugar Resources, Guangxi Liuzhou Luosifen Research Center of Engineering Technology, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545006, China.
Hao ChengGuangxi Key Laboratory of Green Processing of Sugar Resources, Guangxi Liuzhou Luosifen Research Center of Engineering Technology, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545006, China.ORCID 0000-0002-3539-0139

Funding

Hefei University Horizontal Project: Extraction, Application, and Industrialization Process Research of Functional Natural Plant Active Ingredients NONEOpening Project of Guangxi Key Laboratory of Green Processing of Sugar Resources GXTZYKF202308
6 · The paper itself

Abstract

Chlorpheniramine maleate (CPM) is a first-generation antihistamine that is frequently used to treat allergic reactions. However, excessive consumption presents potential health risks. Therefore, it is crucial to develop a quick and precise technique for identifying CPM levels. In this study, nickel cobalt phosphide (NiCoP), a binary metal phosphide, was successfully incorporated into carbon nanofibers. This involved creating a pore structure by adding polyvinylpyrrolidone (PVP) as a pore-forming template to a polyacrylonitrile (PAN) substrate via electrostatic spinning. An innovative electrochemiluminescent sensor for CPM detection was constructed using NiCoP/PVP/PAN carbon nanofibers (NiCoP/PVP/PAN/CNFs). Under optimal conditions, the electrochemical behavior of CPM was studied using NiCoP/PVP/PAN/CNF-modified working electrodes. These findings demonstrate that the three-dimensional porous network architecture of NiCoP/PVP/PAN/CNFs enhances the conductive properties of the material. Consequently, an electrochemical optical sensor fabricated using this structure exhibited remarkable performance. The linear detection range of the sensor was 1 × 10

Indexed as

Acrylic ResinsChlorpheniramineElectrochemical TechniquesLuminescent MeasurementsNanofibersBiosensing TechniquesCarbonElectrodesHumansLimit of DetectionNickelPovidoneAcrylic ResinsCarbonChlorpheniramineNickelpolyacrylonitrilePovidoneelectrochemiluminescenceelectrostatically spun filmNiCoPpolyacrylonitrileporous carbon nanofiber

Identifiers

PMID40572566
PMCPMC12196095

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.