Evidence map›Paper›PMID 40572560›Full record

ArticleMolecules (Basel, Switzerland)2025

Potency Analysis of Semi-Synthetic Cannabinoids in Vaping Oils Using Liquid Chromatography Diode Array Detector with Electrospray Ionization Time-of-Flight Mass Spectrometry for Confirmation of Analyte Identity.

Shaozhong Zhang, Md Mahmud Alam, Brent D Chandler, Jocelyn P Lanorio, Caitlin Deskins, Liguo Song

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shaozhong ZhangDepartment of Chemistry, Western Illinois University, Macomb, IL 61455, USA.
Md Mahmud AlamDepartment of Chemistry, Western Illinois University, Macomb, IL 61455, USA.ORCID 0009-0000-6498-0552
Brent D ChandlerDepartment of Chemistry, Illinois College, Jacksonville, IL 62650, USA.
Jocelyn P LanorioDepartment of Chemistry, Illinois College, Jacksonville, IL 62650, USA.ORCID 0000-0003-4700-6381
Caitlin DeskinsDepartment of Chemistry, Quincy University, Quincy, IL 62301, USA.
Liguo SongDepartment of Chemistry, Western Illinois University, Macomb, IL 61455, USA.ORCID 0000-0002-8147-3381

Funding

National Institute of Justice 15PNIJ-23-GG-04234-RESS, 2023U.S. National Science Foundation CHE-1827209, 2018
6 · The paper itself

Abstract

Since the 2018 Farm Bill legalized hemp, semi-synthetic cannabinoids, typically derived from hemp-extracted CBD, have been marketed as offering a "legal high", raising concerns about consumer safety, labeling, and regulation. Consequently, the potency analysis of these compounds has become increasingly important. To address this need, an LC-DAD method was developed for the quantification of seventeen cannabinoids, selected based on the synthetic pathways of semi-synthetic cannabinoids. These included naturally occurring compounds, semi-synthetic derivatives, and byproducts (CBC, CBD, CBDV, CBG, CBN, CBN-O-acetate, CBT, 9(R)-HHC, 9(S)-HHC, 9(R)-HHC-O-acetate, 9(S)-HHC-O-acetate, Δ

Indexed as

CannabinoidsElectronic Nicotine Delivery SystemsSpectrometry, Mass, Electrospray IonizationVapingChromatography, LiquidCannabinoidselectrospray ionization time-of-flight mass spectrometryliquid chromatography diode array detectorpotency analysissemi-synthetic cannabinoids

Identifiers

PMID40572560
PMCPMC12195824

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.