ArticleMolecules (Basel, Switzerland)2025
Construction of 1,2,3-Triazole-Embedded Polyheterocyclic Compounds via CuAAC and C-H Activation Strategies.
Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Over the past two decades, the copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition (CuAAC), commonly known as click chemistry, and C-H bond activation have gained significant attention and have emerged as key synthetic methodologies. In our efforts to synthesize fused nitrogen-containing heterocycles, we developed a palladium-catalyzed protocol for the synthesis of functionalized 7,10-dihydropyrrolo[3,2,1-ij][1,2,3]triazolo[4,5-c]quinolines and 5,8-dihydrobenzo[3,4][1,2,3]triazolo[4',5':5,6]azepino[1,2-a]indoles from suitable bromo-substituted
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