Evidence map›Paper›PMID 40572525›Full record

ArticleMolecules (Basel, Switzerland)2025

Novel Type I/II Carbazole/Benzindole Photosensitizers Achieve Chemo-Photodynamic Synergistic Therapy for Suppressing Solid Tumors and Drug-Resistant Bacterial Infections.

Zihao Wang, Xiao Liu, Yifan Ma, Jiaxin Zheng, Ke Xu, Yingxue Chang, Zhaoyan Ye, Yong Ling, Lei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zihao WangDepartment of Medicinal Chemistry, School of Pharmacy, Nantong University, Nantong 226001, China.
Xiao LiuDepartment of Medicinal Chemistry, School of Pharmacy, Nantong University, Nantong 226001, China.
Yifan MaDepartment of Medicinal Chemistry, School of Pharmacy, Nantong University, Nantong 226001, China.
Jiaxin ZhengDepartment of Medicinal Chemistry, School of Pharmacy, Nantong University, Nantong 226001, China.
Ke XuDepartment of Medicinal Chemistry, School of Pharmacy, Nantong University, Nantong 226001, China.
Yingxue ChangDepartment of Medicinal Chemistry, School of Pharmacy, Nantong University, Nantong 226001, China.
Zhaoyan YeDepartment of Medicinal Chemistry, School of Pharmacy, Nantong University, Nantong 226001, China.
Yong LingDepartment of Medicinal Chemistry, School of Pharmacy, Nantong University, Nantong 226001, China.
Lei WangDepartment of Medicinal Chemistry, School of Pharmacy, Nantong University, Nantong 226001, China.ORCID 0000-0002-6155-6892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the clinical challenges posed by symbiotic drug-resistant bacterial infections and tumor microenvironments, this study designed and synthesized novel carbazole/benzindole-based photosensitizers

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsCarbazolesIndolesNeoplasmsPhotochemotherapyPhotosensitizing AgentsAnimalsHT29 CellsHumansMethicillin-Resistant Staphylococcus aureusMiceMicrobial Sensitivity TestsReactive Oxygen SpeciesXenograft Model Antitumor AssaysAnti-Bacterial AgentsAntineoplastic AgentscarbazoleCarbazolesIndolesPhotosensitizing AgentsReactive Oxygen Speciesdrug-resistant bacterial infectionMRSAphotodynamic therapy (PDT)reactive oxygen species (ROS)tumor microenvironment

Identifiers

PMID40572525
PMCPMC12195977

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.