ReviewMolecules (Basel, Switzerland)2025
Phytosterols: Extraction Methods, Analytical Techniques, and Biological Activity.
Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Dietary and Formulation Potential of Natural Oils and Fats in Ocular Health and Disease: Mechanisms, Evidence, and Future Directions.Nutrients · 2026Review
- From Detoxified Yam to Bioactive Extracts: Integrated Extraction and In Silico Evidence of Anti-Biofilm Activity ofLife (Basel, Switzerland) · 2026Article
- Synthesis and Stereochemical Assignment of Diastereomeric Steroidal Spiro-1,2,4-trioxolanes with Sitostanone Motif Using PLS2 Chemometric Analysis of DFT-Calculated and ExperimentalMolecules (Basel, Switzerland) · 2026Article
- Phytosteryl Esters Encapsulated in Liposomes as Bioactive Additives in Mayonnaise.Molecules (Basel, Switzerland) · 2026Article
- The Chemical Structures, Neuroprotective Effects, Structure-Activity Relationships, and Applications of Flavonoids, Phenolic Acids, Terpenoids, and Sterols in Dandelion: A Review.Food science & nutrition · 2026Review
- Unlocking the Power of Plant-Derived Natural Products: Therapeutic Benefits for Cognitive Health and Neuropsychiatric Symptoms in Dementia-Related Diseases.Plants (Basel, Switzerland) · 2026Review
- GC-MS profiling, biological activities and molecular docking of total sterol extracts from Pontederia crassipes (Lake Tana, Ethiopia).Scientific reports · 2026Article
- Phytosterol Profiling as a Tool for Edible Oil Authentication: Challenges and Prospects.Foods (Basel, Switzerland) · 2026Review
- Toward Sustainable Testosterone Manufacturing: Green Chemistry and Microbial Biotransformation Approaches.International journal of molecular sciences · 2026Review
- Anticancer Molecular Mechanisms of Phytosterols: An Updated Review on Clinical Trials.Food science & nutrition · 2026Review
- Varietal Discrimination of Purple, Red, and White Rice Bran Oils Based on Physicochemical Properties, Bioactive Compounds, and Lipidomic Profiles.Molecules (Basel, Switzerland) · 2026Article
- Dual Action of Ivy and Strawberry Essential Oils: Induction ofInternational journal of molecular sciences · 2025Article
- Glauconite: A Natural Ally in Cancer Prevention and Treatment.Archives of Razi Institute · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phytosterols, essential components of plant cell membranes, are abundant in fruits, vegetables, nuts, and seeds. Among them, β-sitosterol, campesterol, and stigmasterol have drawn significant interest for their well-documented biological activities. This review highlights recent advancements in extraction and analytical methods aimed at improving phytosterol yield, maintaining chemical stability, and reducing environmental impact. These innovative, eco-friendly techniques offer promising alternatives to traditional extraction approaches and hold potential for industrial-scale use. Phytosterols possess various bioactive properties, including antioxidant, anti-inflammatory, chemopreventive, cholesterol-lowering, and neuroprotective effects. Through these mechanisms, dietary phytosterols may help prevent cardiovascular and neurodegenerative diseases, type 2 diabetes, and certain cancers. Recent studies have focused on the identification, isolation, purification, and characterization of phytosterols from diverse food matrices, along with assessing their health benefits. However, the specific molecular pathways responsible for their pharmacological actions remain poorly understood, highlighting the need for further research, particularly in human clinical trials. This review provides a comprehensive overview of the extraction strategies, biological functions, and mechanisms of action of phytosterols, offering valuable insights for developing phytosterol-enriched functional foods and nutraceuticals.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.