Evidence map›Paper›PMID 40572076›Full record

ArticleMicroorganisms2025

Chlorophyllin-Mediated Photodynamic Inactivation: Dosage and Time Dependency in the Inhibition of

Sarah Pohland, Jana Vourvoutsiotou, Leah Brandtner, David Geißler, Selina Wiesmeth, Vanessa Scudlo, Peter Richter, Andreas Burkovski, Michael Lebert

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah PohlandCell Biology Division, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.
Jana VourvoutsiotouCell Biology Division, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.ORCID 0009-0004-1108-3179
Leah BrandtnerCell Biology Division, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.
David GeißlerCell Biology Division, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.
Selina WiesmethCell Biology Division, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.
Vanessa ScudloCell Biology Division, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.
Peter RichterCell Biology Division, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.
Andreas BurkovskiMicrobiology Division, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.ORCID 0000-0003-1896-4521
Michael LebertCell Biology Division, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany.ORCID 0000-0002-0448-8117

Funding

Deutsches Zentrum für Luft- und Raumfahrt (DLR), BMWi project 50WB1923
6 · The paper itself

Abstract

Photodynamic inactivation of bacteria offers a promising alternative to counteract the trend towards the development of resistance, which, if left uncontrolled, will lead to the death of 10 million people per year by 2050. Its advantage over antibiotics is the site-specific mode of action due to the photosensitizer (PS) and the low risk of developing resistance. This is primarily prevented by the damage of the bacteria, which also destroy internal structures such as nucleic acid, proteins, and lipids. A promising and still little-researched PS is chlorophyllin (CHL), a chlorophyll derivative. This study investigated its mode of action on

Indexed as

antibiotic alternativeschlorophyllinphotodynamic inactivation (PDI)photodynamic therapy (PDT)photosensitizer

Identifiers

PMID40572076
PMCPMC12195115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.