Evidence map›Paper›PMID 40572055›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Subjective cognitive decline among diverse older adults: Prevalence and associations with objective cognition.

Sarah Tomaszewski Farias, Iris Leng, Kathryn Papp, Anika Mehra, Michelle Chan, Michelle York, Bonnie C Sachs, Kristin R Krueger, Athene Lee, Rachel Whitmer and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03688126 (U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03688126 nacompletednot on this map

U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk

TypeinterventionalSponsorWake Forest University Health SciencesRan2019 to 2025Enrolled2,000ConditionsAlzheimer DiseaseArmsSelf-Guided Lifestyle Intervention, Structured Lifestyle Intervention
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
  2. Review
  3. Subjective cognitive complaints in cognitively unimpaired Parkinson's disease: Associations with affective burden, motor severity, and awareness-related processes.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  4. Lifecourse socioeconomic status and subjective cognitive decline among diverse older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. How culture shapes subjective cognitive decline reporting: Refining assessment tools with digital solutions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  9. Subjective cognitive decline among diverse older adults: Prevalence and associations with objective cognition.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sarah Tomaszewski FariasDepartment of Neurology, University of California Davis, Sacramento, California, USA.
Iris LengDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Kathryn PappDepartment of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Anika MehraDepartment of Public Health Sciences, University of California Davis, Sacramento, California, USA.
Michelle ChanDepartment of Neurology, University of California Davis, Sacramento, California, USA.
Michelle YorkDepartment of Neurology, Baylor College of Medicine, Houston, Texas, USA.
Bonnie C SachsDepartment of Neurology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Kristin R KruegerDepartment of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Athene LeeButler Hospital, Memory and Aging Program, and Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Rachel WhitmerDepartment of Public Health Sciences, University of California Davis, Sacramento, California, USA.
Heather M SnyderDivision of Medical and Scientific Relations, Alzheimer's Association, Chicago, Illinois, USA.
Laura D BakerDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.
U.S. POINTER Study Group

Funding

Wake Forest University School of Medicine Alzheimer's Disease Research CenterP30AG072947 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SUZANNE CRAFT · 2021 to 2026
$24.3M
Alzheimer's Association POINTER-19-611541NIA NIH HHS P30 AG072947
6 · The paper itself

Abstract

introductionSubjective cognitive decline (SCD) may precede objective cognitive impairment. We examined prevalence, type of SCD, and associations with neuropsychological measures among diverse older adults.

methodsThe sample included older adults from three ethnoracial groups enrolled in the U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk (POINTER) trial. Everyday Cognition (ECog) measured SCD, and neuropsychological function was assessed using global memory, executive function, and processing speed composites.

resultsHispanic/Latinx participants were more likely to report SCD than non-Hispanic White (NHW) or Black participants, particularly executive function concerns. In the full sample, adjusting for demographics and depression, SCD ratings were associated with most neuropsychological outcomes. In analyses stratified by ethnoracial group, SCD ratings were associated with many of the neuropsychological domains in NHW participants and with processing speed among Black participants; no association was observed in Hispanic/Latinx participants. DISCUSSION: Prevalence, type of SCD, and associations with cognition varied by ethnoracial group. CLINICAL TRIAL REGISTRATION NUMBER: NCT03688126 (ClinicalTrials.gov). HIGHLIGHTS: Hispanic/Latinx participants endorsed greater subjective cognitive decline (SCD) than other ethnoracial groups. Hispanic/Latinx participants were more likely to endorse executive function concerns. SCD was associated with several neuropsychological domains in non-Hispanic White participants. SCD was related to processing speed for Black participants. SCD was unrelated to objective cognitive performance in Hispanic/Latinx participants.

Indexed as

CognitionCognitive DysfunctionAgedAged, 80 and overBlack or African AmericanExecutive FunctionFemaleHispanic or LatinoHumansMaleMulticenter Studies as TopicNeuropsychological TestsPrevalenceRandomized Controlled Trials as TopicUnited StatesWhiteagingAlzheimer's diseasecognitionethnoracial differencesmemory complaintsrisk factorssubjective cognitive concernssubjective cognitive decline

Identifiers

PMID40572055
PMCPMC12202460

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.