Evidence map›Paper›PMID 40571995›Full record

ReviewRadiation research2025

Centers for Medical Countermeasures against Radiation Consortium: Past, Present, and Beyond.

Lanyn P Taliaferro, David J Brenner, Sally A Amundson, Guy Garty, Yuji Zhang, Erika W Davies, France Carrier, Joel R Ross, J Mark Cline, Nelson J Chao

Abstract readReview
In one paragraph

Review in Radiation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lanyn P Taliaferro
David J Brenner
Sally A Amundson
Guy Garty
Yuji Zhang
Erika W Davies
France Carrier
Joel R Ross
J Mark Cline
Nelson J Chao

Funding

Sample Engineering CoreU19AI067773 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AMUNDSON, SALLY A. · 2005 to 2024
$105.4M
Somatostatin analogues as countermeasures against intestinal radiation toxicityU19AI067798 · NIAID · DUKE UNIVERSITY · PI CHAO, NELSON J. · 2005 to 2024
$82.1M
The Wake Forest Nonhuman Primate Radiation Survivor CohortU01AI150578 · NIAID · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI J. MARK CLINE · 2020 to 2026
$23.7M
Preclinical Evaluation of Radioprotectin-1 for Mitigation of GI-ARSU19AI150574 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI TIGYI, GABOR J · 2020 to 2024
$13.0M
Intramural NIH HHS Z99 AI999999NIAID NIH HHS U01 AI150578NIAID NIH HHS U19 AI067773NIAID NIH HHS U19 AI067798NIAID NIH HHS U19 AI150574
6 · The paper itself

Abstract

The Centers for Medical Countermeasures against Radiation Consortium (CMCRC) has provided a strong research foundation for the radiobiology science that will follow. After 20 years, however, the CMCRC will continue to conduct research on preparedness in niche areas of radiobiology and advanced product development, many of which were initiated by the CMCRC. This manuscript offers a review of past and current strategies and advancements in medical countermeasures to address radiation injuries, carried out by the CMCRC and funded by the National Institute of Allergy and Infectious Diseases Radiation and Nuclear Countermeasures Program. It also explores the mechanisms of radiation-induced injuries, discusses existing medical countermeasures, and highlights emerging technologies and potential future directions for radiobiology researchers. This review aims to enhance our understanding of current medical countermeasures against radiation and contribute to the future development of more efficient and innovative approaches to mitigate and treat radiation-induced damage.

Indexed as

Medical CountermeasuresRadiation InjuriesRadiobiologyAnimalsHumansModels, AnimalRadiometry

Identifiers

PMID40571995
PMCPMC12344595

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.