Evidence map›Paper›PMID 40571984›Full record

ArticleJournal of forensic sciences2025

Micro-CT for the differentiation between live birth and stillbirth: A pilot study.

Giovanni Botta, Tullio Genova, Alessandro Bonsignore, Francesca Buffelli, Federico Davide Mussano, Francesco Lupariello

Abstract read
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Article in Journal of forensic sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Giovanni BottaA.O.U. Città della Salute e della Scienza-Anatomia Patologica U, Sezione Materno-Fetale-Pediatrica, Torino, Italy.
Tullio GenovaDepartment of Life Sciences and Systems Biology, UNITO, Turin, Italy.
Alessandro BonsignoreSection of Legal and Forensic Medicine, Department of Health Sciences (DISSAL), University of Genova, Genova, Italy.ORCID https://orcid.org/0000-0001-6616-0347
Francesca BuffelliFetal-Perinatal Pathology Unit, IRCCS-Istituto Giannina Gaslini, Genova, Italy.
Federico Davide MussanoCIR Dental School, Department of Surgical Sciences, UNITO, Turin, Italy.
Francesco LuparielloLegal Medine Unit, Department of Public Health and Paediatrics, University of Turin, Turin, Italy.ORCID https://orcid.org/0000-0003-2264-8521

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The distinction between live births and stillbirths is crucial for determining the appropriate legal consequences. Historically, researchers have operated under the principle that an infant's lungs will be filled with air upon death, whereas a fetus's lungs will not. The flotation test for the lungs is the primary method still used in many jurisdictions. However, there are concerns regarding its reliability. For this reason, we conducted a pilot study to evaluate the feasibility of postmortem micro-computed tomography (micro-CT) for differentiating between formalin-fixed aerated and nonaerated lungs. Lung samples from aerated (Group 1) and nonaerated (Group 2) subjects were scanned using micro-CT. We calculated the gas volume percentage (GV%) in each sample. Group 1 (aerated lungs) showed a mean GV% of 9.52 ± 6.77, while Group 2 (nonaerated lungs) showed a mean GV% of 0.58 ± 0.66. These findings suggest that micro-CT can qualitatively and quantitatively detect pulmonary aeration and may serve as a valuable tool in forensic investigations involving suspected neonaticide, feticide, and intrauterine fetal demise.

Indexed as

Live BirthLungStillbirthX-Ray MicrotomographyFeasibility StudiesFemaleForensic PathologyHumansInfant, NewbornPilot ProjectsPregnancyflotation testforensic pathologyinfanticideintrauterine fetal demiselive birthmicro‐CTneonaticidestillbirth

Identifiers

PMID40571984
PMCPMC12584126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.