Evidence map›Paper›PMID 40571973›Full record

ReviewFEBS letters2025

Single-cell insights into the role of T cells in B-cell malignancies.

Laura Llaó-Cid

Abstract readReview
In one paragraph

Review in FEBS letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Laura Llaó-CidInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.ORCID https://orcid.org/0000-0003-0543-6084

Funding

Agencia Estatal de Investigacin JDC2022 048571I
6 · The paper itself

Abstract

The intricate interplay between T cells and tumor cells in B-cell malignancies has garnered significant attention in recent years. Single-cell technologies have revolutionized our understanding of this dynamic relationship, offering unprecedented resolution and insights into cellular heterogeneity, signaling pathways, and immune interactions. This review synthesizes the recent findings that single-cell methodologies have elucidated on the roles of T cells in the pathogenesis, progression, and therapeutic response of B-cell malignancies. Key discoveries include the identification of previously unknown T-cell subsets and their functional states, as well as the mechanisms of immune evasion by malignant B cells. These insights pave the way for innovative therapeutic strategies aimed at harnessing the immune system to combat B-cell lymphomas.

Indexed as

B-LymphocytesLymphoma, B-CellSingle-Cell AnalysisT-LymphocytesAnimalsHumansSignal TransductionB‐NHLimmunotherapysingle‐cell analysesT‐cell heterogeneitytumor microenvironment

Identifiers

PMID40571973
PMCPMC12558677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.