Evidence map›Paper›PMID 40571930›Full record

ArticleBMC public health2025

NorthPop: a prospective population-based birth cohort study.

Christina E West, Pernilla Lif Holgerson, Anna Chmielewska, Richard Lundberg-Ulfsdotter, Carina Lagerqvist, Elisabeth Stoltz Sjöström, Katharina Wulff, Olof Sandström, Ingrid Mogren, Sven Arne Silfverdal and 1 more

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
  2. Prenatal Air Pollution Exposure During Late Pregnancy Associates With Food Sensitization at 18 Months.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  3. Article
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  9. Maternal dietary inflammatory index during pregnancy and the risk of offspring allergic disease.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christina E WestDepartment of Clinical Sciences, Pediatrics, Umeå University, 901 85, Umeå, Sweden. christina.west@umu.se.
Pernilla Lif HolgersonDepartment of Odontology, Pedodontics, Umeå University, Umeå, Sweden.
Anna ChmielewskaDepartment of Clinical Sciences, Pediatrics, Umeå University, 901 85, Umeå, Sweden.
Richard Lundberg-UlfsdotterDepartment of Clinical Sciences, Pediatrics, Umeå University, 901 85, Umeå, Sweden.
Carina LagerqvistDepartment of Clinical Sciences, Pediatrics, Umeå University, 901 85, Umeå, Sweden.
Elisabeth Stoltz SjöströmDepartment of Food, Nutrition and Culinary Science, Umeå University, Umeå, Sweden.
Katharina WulffDepartment of Molecular Biology, Umeå University, Umeå, Sweden.
Olof SandströmDepartment of Clinical Sciences, Pediatrics, Umeå University, 901 85, Umeå, Sweden.
Ingrid MogrenDepartment of Clinical Sciences, Obstetrics and Gynecology, Umeå University, Umeå, Sweden.
Sven Arne SilfverdalDepartment of Clinical Sciences, Pediatrics, Umeå University, 901 85, Umeå, Sweden.
Magnus DomellöfDepartment of Clinical Sciences, Pediatrics, Umeå University, 901 85, Umeå, Sweden. magnus.domellof@umu.se.

Funding

County Council of Region Västerbotten RV-1006561County Council of Region Västerbotten RV 548591County Council of Region Västerbotten RV 832 441County Council of Region Västerbotten RV 992 551Ekhagastiftelsen 2018-40Forskningsrådet om Hälsa, Arbetsliv och Välfärd 2024-01645Hjärt-Lungfonden 20180641Kempestiftelserna JCSMK23-0155Umeå Universitet FS 2.1.6.2-44-15Vetenskapsrådet 2016-02095Vetenskapsrådet 2018-02642
6 · The paper itself

Abstract

backgroundNon-communicable diseases (NCDs) are a global health issue, posing a substantial burden on the individual, community, and public health. The risk of developing NCDs is influenced by a complex interplay between genetic, epigenetic, and environmental factors.

methodsThe NorthPop Birth Cohort Study (NorthPop) constitutes an infrastructure enabling cutting-edge research on the foundational pathways to NCDs in childhood, including allergic diseases and asthma, overweight/obesity, cognitive and neurodevelopmental dysfunction, gastrointestinal disorders, and caries. NorthPop aims at recruiting 10,000 families. Pregnant women and their partners residing in Västerbotten County, Sweden are eligible. Recruitment started in 2016 and is anticipated to end in 2025. Extensive data on parental, fetal and child health outcomes, lifestyle, diet, and environmental exposures are prospectively collected using web-based questionnaires in pregnancy and childhood until the children turn 7 years old. Urine samples are collected from the pregnant woman at gestational age 14-24 weeks. Blood samples are collected at gestational age 28 weeks. Placenta and cord blood are collected at birth. A breast milk sample is collected 1 month postpartum. Blood samples from the children are collected at 18 months and 7 years of age. Oral swabs and fecal samples are collected from the children within 48 h of birth, at 1, 9 and 18 months, 3 and 7 years of age. At age 7 years, children are invited to a follow-up visit, including measurements of weight, height, blood pressure, pulse, hand grip strength, working memory, skin prick test and saliva sampling. Additional measurements, such as sleep-wake and light exposure, and additional biological samples are collected in sub-cohorts. Permission for linkage to medical records and national registers e.g., the Swedish Pregnancy Register, the National Patient Register, the Longitudinal Integration Database for Health insurance and Labor market studies and the Swedish Prescribed Drug Register has been granted. DISCUSSION: Our multidisciplinary approach allows us to study how early life exposures, as well as parental health and lifestyle, influence future health in the offspring. Our results are anticipated to contribute to the understanding of disease risk and may inform future strategies aimed at risk reduction, highly significant for public health.

trial registrationRetrospectively registered at Researchweb 11 November 2024 (project number 279272).

Indexed as

Birth CohortAdultChildChild, PreschoolFemaleHumansInfantInfant, NewbornMalePregnancyProspective StudiesSurveys and QuestionnairesSwedenChildrenDevelopmental originsEnvironmentEpidemiologyNon-communicable diseasesNutritionObstetricsProgrammingRisk factors

Identifiers

PMID40571930
PMCPMC12199497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.