Evidence map›Paper›PMID 40571927›Full record

ArticlePopulation health metrics2025

The impact of the COVID-19 pandemic on all-cause mortality and life expectancy in northern Ghana: findings from the Navrongo Health and Demographic Surveillance System.

Daniel K Azongo, Timothy Awine, Chodziwadziwa W Kabudula, Samuel Oladokun, Beth A Tippett Barr, Jean Bashingwa, Bawa Ayaga, Mumuni Abu, Patrick Adum Ansah

Abstract read
In one paragraph

Article in Population health metrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel K AzongoNavrongo Health Research Center, Ghana Health Service, Navrongo, Ghana. kdazongo@gmail.com.ORCID 0000-0002-0210-3906
Timothy AwineNavrongo Health Research Center, Ghana Health Service, Navrongo, Ghana.
Chodziwadziwa W KabudulaMRC/Wits Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Samuel OladokunNavrongo Health Research Center, Ghana Health Service, Navrongo, Ghana.
Beth A Tippett BarrOffice of the Director, Nyanja Health Research Institute, Salima, Malawi.
Jean BashingwaMRC/Wits Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Bawa AyagaRegional Institute of Population Studies, University of Ghana, Accra, Ghana.
Mumuni AbuRegional Institute of Population Studies, University of Ghana, Accra, Ghana.
Patrick Adum AnsahNavrongo Health Research Center, Ghana Health Service, Navrongo, Ghana.

Funding

Bill and Melinda Gates Foundation INV-050361Gates Foundation INV-030309
6 · The paper itself

Abstract

backgroundMeasurement of excess mortality attributable to the COVID-19 pandemic is essential for quantifying the direct and indirect effects on mortality and informing future public health control strategies. This study assessed the impact of COVID-19 on excess mortality and life expectancy at birth in rural northern Ghana.

methodsData was obtained from the Navrongo Health and Demographic Surveillance System (NHDSS) in Ghana. We computed the number of deaths and person-years contributed from January 1, 2015, to December 31, 2021, and estimated mortality rates for each year, age group, and gender. Mortality rate differences were calculated by comparing the period before (2018-2019) and during (2020-2021) the pandemic. To estimate excess mortality, a generalised additive model was fitted to the historical data from 2015 to 2019 to predict the expected mortality rates in the COVID-19 period (2020-2021). A Cox proportional hazards model was fitted to assess the risk factors associated with mortality, adjusting for socio-demographic variables. Conventional life table techniques were used to estimate period life expectancy at birth for males and females.

resultsOverall, 12,413 deaths and 1,227,115 person-years were included in the analysis. This consists of 5,930 (49%) deaths and 572,963 person-years for the pre-pandemic period (2015-2019) and 6,483 (52%) deaths and 654,153 person-years for the pandemic period (2020-2021). From 2020 to 2021, the crude mortality rate was 23.9 deaths per 1000 person-years compared with 20.7 deaths per 1000 person-years predicted if COVID-19 had not occurred. COVID-19 also caused a decline in life expectancy at birth, especially in males, by 3.4 years. In addition, the adjusted risk of dying during the pandemic was higher in males (12.1%) compared to females and higher in the 65 + years age group (69.2%) compared to the younger population.

conclusionThe COVID-19 pandemic caused an increase in deaths and a decrease in life expectancy in the NHDSS population in Ghana, particularly among men and those aged 65 years and older. These results reinforce the critical role of routine surveillance data in assessing the impact of public health emergencies such as the COVID-19 pandemic and informing public health strategies.

Indexed as

COVID-19Life ExpectancyMortalityAdolescentAdultAgedAged, 80 and overCause of DeathChildChild, PreschoolFemaleGhanaHumansInfantInfant, NewbornMaleCoronavirusCOVID-19Excess mortalityHealth and Demographic Surveillance SitesLife expectancyMortality

Identifiers

PMID40571927
PMCPMC12199484

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.