Evidence map›Paper›PMID 40571855›Full record

ArticleWorld journal of microbiology & biotechnology2025

Quorum quenching of phenolic compounds from Leptolyngbya spp. MACC 32 via downregulation of the periplasmic receptor LuxP in Vibrio harveyi: Hinting a putative mechanism.

Madiyan Saranya, Byeol Ryu, Jose Seena, Bhaskaran Silpa, Ameer Ahna, C Benjamin Naman, Evgenia Glukhov, T P Sajeevan, I S Bright Singh, William H Gerwick and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Madiyan SaranyaNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin-16, Kerala, 682016, India.
Byeol RyuScripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, MC 0212, La Jolla, CA, 92093-0212, USA.
Jose SeenaNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin-16, Kerala, 682016, India.
Bhaskaran SilpaNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin-16, Kerala, 682016, India.
Ameer AhnaNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin-16, Kerala, 682016, India.
C Benjamin NamanScripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, MC 0212, La Jolla, CA, 92093-0212, USA.
Evgenia GlukhovScripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, MC 0212, La Jolla, CA, 92093-0212, USA.
T P SajeevanNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin-16, Kerala, 682016, India.
I S Bright SinghNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin-16, Kerala, 682016, India.
William H GerwickScripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, MC 0212, La Jolla, CA, 92093-0212, USA.
Joseph ValsammaNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin-16, Kerala, 682016, India. valsamma@cusat.ac.in.

Funding

DBT-Bioinformatics Centre - Department of Biotechnology, India (BT/PR40221/BTIS/137/10/2021 dated 22/2/2021DST-INSPIRE DST/INSPIRE/03/2016/001956Scheme for Promotion of Academic and Research Collaboration SPARC/2019-2020/P2547/SL
6 · The paper itself

Abstract

Vibrio harveyi causes vibriosis, leading to high mortality and economic loss in global aquaculture. Quorum sensing (QS) driven biofilm formation makes them more resistant to various control measures. This study examined QS inhibition (QSI) of V. harveyi LB3 using marine cyanobacterial natural products. Qualitative and quantitative (88%) assays confirmed the quorum quenching (QQ) efficiency of the intracellular component of Leptolyngbya spp. MACC 32. The active fraction (E3) of the extract showed less than 50% toxicity to PmLyo-Sf9 cells and brine shrimp at 1 mg mL

Indexed as

Bacterial ProteinsPhenolsQuorum SensingVibrioAnimalsAnti-Bacterial AgentsArtemiaBiofilmsDown-RegulationGene Expression Regulation, BacterialMicrobial Sensitivity TestsMolecular Docking SimulationTrans-ActivatorsAnti-Bacterial AgentsBacterial ProteinsPhenolsTrans-Activators4-Hydroxybenzaldehyde (4-HBAL)4-hydroxybenzoic acid (4-HBA)LeptolyngbyaQuorum quenching (QQ)Vibrio harveyiVibriosis

Identifiers

PMID40571855

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.