Evidence map›Paper›PMID 40571803›Full record

ReviewNature protocols2025

Sonoafterglow nanoprobes for deep-tissue imaging of peroxynitrite.

Cheng Xu, Jingsheng Huang, Kanyi Pu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cheng XuSchool of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore.ORCID 0000-0002-5838-7979
Jingsheng HuangSchool of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore.ORCID 0009-0002-1274-7219
Kanyi PuSchool of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore. kypu@ntu.edu.sg.ORCID 0000-0002-8064-6009

Funding

Singapore Ministry of Education Academic Research FundSingapore National Research Foundation
6 · The paper itself

Abstract

Optical imaging of tumor biomarkers provides key diagnostic information about tumor status. Light-induced afterglow (photoafterglow) imaging provides a higher signal to background ratio than typical fluorescence imaging; however, both modalities face challenges in detecting biomarkers in deep tissues owing to the limited penetration depth of light. Here we provide instructions for synthesizing ultrasound-induced afterglow (sonoafterglow) nanoprobes (SNAP) for the deep-tissue imaging of peroxynitrite (ONOO

Indexed as

NanoparticlesOptical ImagingPeroxynitrous AcidAnimalsHumansMiceTumor MicroenvironmentPeroxynitrous Acid

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.