Evidence map›Paper›PMID 40571794›Full record

SynthesisSurgical endoscopy2025

Higher BMI increases risk of stoma-site incisional hernia and other complications following diverting loop ileostomy and reversal: a systematic review and meta-analysis.

Kaiser O'Sahil Sadiq, Swetha Lakshminarayanan, Patricia Ruiz Cota, Eugenia Marquez Castillo

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kaiser O'Sahil SadiqDepartment of Surgery, UC San Diego, San Diego, CA, USA. kaiserosahil@gmail.com.ORCID https://orcid.org/0009-0006-5050-6626
Swetha LakshminarayananDepartment of Surgery, UC San Diego, San Diego, CA, USA.
Patricia Ruiz CotaDepartment of Surgery, UC San Diego, San Diego, CA, USA.
Eugenia Marquez CastilloDepartment of Surgery, Abington Jefferson Hospital, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiverting loop ileostomies (DLI) are commonly used to protect high-risk anastomoses. While a higher body mass index (BMI) is known to increase postoperative morbidity, its specific effect on DLI-related complications is less well understood.

methodsThis systematic review and meta-analysis followed PRISMA guidelines, and Cochrane Library, Embase, PubMed, and Google Scholar were searched for English publications without time restrictions. Statistical analysis was performed using Meta-Mar v3.5.1.

resultsOut of 586 studies yielded and 6 manually retrieved, 26 were included, totaling 5,141 patients (53.5% male). The mean ages were 35.0-65.3 years, and the mean BMI was 19.8-27.1 kg/m

conclusionIncreased BMI is a risk factor for certain DLI-related complications, particularly stoma-site incisional hernia. If feasible, mesh placement at the ileostomy site should be strongly considered for patients with a BMI > 25 to reduce the risk of stoma-site incisional hernia. Weight loss prior to DLI and reversal should be encouraged.

Indexed as

Body Mass IndexIleostomyIncisional HerniaPostoperative ComplicationsHumansRisk FactorsSurgical StomasBMIComplicationsDiverting loop ileostomyMorbidityObesityStoma

Identifiers

PMID40571794
PMCPMC12287187

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.