Evidence map›Paper›PMID 40571758›Full record

ArticleClinical neuroradiology2025

Isochrone-based Identification of Gaps in Neurovascular Care in Germany.

Marius Vach, Christian Rubbert, Julian Caspers, Sven G Meuth, Marc Pawlitzki, Lars Masanneck

Abstract read
In one paragraph

Article in Clinical neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marius VachInstitute for Diagnostic and Interventional Radiology, University Hospital and Medical Faculty University Hospital Düsseldorf, Duesseldorf, Germany.
Christian RubbertInstitute for Diagnostic and Interventional Radiology, University Hospital and Medical Faculty University Hospital Düsseldorf, Duesseldorf, Germany.
Julian CaspersInstitute for Diagnostic and Interventional Radiology, University Hospital and Medical Faculty University Hospital Düsseldorf, Duesseldorf, Germany.
Sven G MeuthDepartment of Neurology, University Hospital and Medical Faculty University Hospital Düsseldorf, Heinrich-Heine University Duesseldorf, Moorenstraße 5, 40225, Duesseldorf, Germany.
Marc PawlitzkiDepartment of Neurology, University Hospital and Medical Faculty University Hospital Düsseldorf, Heinrich-Heine University Duesseldorf, Moorenstraße 5, 40225, Duesseldorf, Germany.
Lars MasanneckDepartment of Neurology, University Hospital and Medical Faculty University Hospital Düsseldorf, Heinrich-Heine University Duesseldorf, Moorenstraße 5, 40225, Duesseldorf, Germany. Lars.Masanneck@med.uni-duesseldorf.de.

Funding

Deutsche Forschungsgemeinschaft 493659010Medizinische Fakultät, Heinrich-Heine-Universität Düsseldorf n/aMinisterium für Wirtschaft, Innovation, Digitalisierung und Energie des Landes Nordrhein-Westfalen 005-2008-0055
6 · The paper itself

Abstract

purposeModern endovascular techniques enable the treatment of various neurovascular diseases. Given the complexity of these interventions, a certification system was introduced to ensure standardized care at specialized treatment centers. We used a driving-time-based isochrone approach to identify care gaps in different German Society of Interventional Radiology (DeGIR) certified neurovascular treatment centers.

methodsDeGIR-certified neurovascular centers for minimally invasive stroke care (module E), neurovascular vessel anomalies (module F), and neurovascular therapy (module EF) were geocoded and driving-time-based isochrones were calculated for 30, 60, 90, and 120 min. The resulting contours were aggregated and combined with the 2025 population estimates from the Global Human Settlement Layer to estimate residents' access.

resultsThe analysis identified gaps in under-60-minute reachability, notably in northeastern Germany and parts of Rhineland-Palatinate, Saarland, and the southwest, with modules EF and F most affected, while module E fared better. Within 120 min, coverage was nearly complete across all modules. On a population level, 59.4% of residents lived within 30 min, 92.81% within 60 min, and 99.98% within 120 min of a module E center. Module F reached 45.8%, 84.26%, and 99.73%, respectively, with module EF showing intermediate accessibility. DISCUSSION: The driving-time-based isochrone approach identifies regions where access to specialized neurovascular care is limited-a critical issue in emergencies like stroke or aneurysm hemorrhage. Although immediate stroke care is generally more accessible than care for neurovascular anomalies, thrombectomy within an acceptable timeframe is not available to the entire population. These findings can guide strategies to enhance neurovascular care across Germany.

Indexed as

Cerebrovascular DisordersEndovascular ProceduresHealth Services AccessibilityStrokeCertificationGermanyHumansGermanyIntracranial hemorrhageIsochrone analysisNeurovascular diseaseStroke

Identifiers

PMID40571758
PMCPMC12552351

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.