Evidence map›Paper›PMID 40571749›Full record

ArticleLab animal2025

Murine astrovirus infection course and antibody response in different mouse strains.

Jessica Seib, Daniela Höfler, Lena Hornetz, Nicole Ohl, Katrin Götz, Klaus Vogel, Julia Butt, Katja Schmidt

Abstract read
In one paragraph

Article in Lab animal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jessica SeibMicrobiological Diagnostics, German Cancer Research Center, Heidelberg, Germany.
Daniela HöflerInfections and Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
Lena HornetzCentral Animal Laboratory, Center for Preclinical Research, German Cancer Research Center, Heidelberg, Germany.
Nicole OhlMicrobiological Diagnostics, German Cancer Research Center, Heidelberg, Germany.
Katrin GötzMicrobiological Diagnostics, German Cancer Research Center, Heidelberg, Germany.
Klaus VogelMicrobiological Diagnostics, German Cancer Research Center, Heidelberg, Germany.
Julia ButtInfections and Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
Katja SchmidtMicrobiological Diagnostics, German Cancer Research Center, Heidelberg, Germany. katja.schmidt@dkfz-heidelberg.de.ORCID 0000-0002-4828-7974

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monitoring the health of mice used in animal experiments constitutes an important instrument toward microbiological standardization, as infections can alter physiological parameters and immune reactions and may therefore have an essential impact on experimental outcome. In view of the high prevalence rates of murine astrovirus (MuAstV) infections in laboratory mouse facilities worldwide and the potential impact on research outcomes and reproducibility, there is a need to include MuAstV in the existing laboratory mice health monitoring programs. Here, to determine the sentinel strain and diagnostic method of choice, we aimed to assess the course of MuAstV infection and the resulting immune response in three immunocompetent mouse strains (Crl:CD1 (ICR), C57BL/6J and BALB/cOlaHsd) and one immunodeficient strain (NOD.Cg-Prkdc

Indexed as

Antibodies, ViralAntibody FormationAstroviridae InfectionsMamastrovirusRodent DiseasesAnimalsFecesFemaleMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, Inbred NODSpecies SpecificityViral LoadVirus SheddingAntibodies, Viral

Identifiers

PMID40571749
PMCPMC12213600

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.