ArticleJournal of cosmetic dermatology2025
Optimizing Botulinum Toxin Injections in the Platysma Muscle Based on Motor Nerve Distribution.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Unexpected Botulinum Toxin Effect on Neck Rejuvenation After a Jawline Lifting Procedure: A Case Report.Cureus · 2026Article
- Italian Consensus and Review in Lower Face Mimetic Muscle Treatment with Botulinum Toxin-A.Toxins · 2026Review
- Ultrasound imaging in aesthetic medicine: safety and precision in injectable procedures.Journal of ultrasound · 2026Review
- Neural Distribution-Guided Botulinum Toxin Injection for Platysma muscle: A Split-Neck Comparison With Conventional Technique.Journal of cosmetic dermatology · 2026Article
- Optimizing Botulinum Toxin Injections in the Platysma Muscle Based on Motor Nerve Distribution.Journal of cosmetic dermatology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlatysmal bands contribute to neck ageing and lower-face descent. Although botulinum toxin A (BoNT-A) is approved for this indication, conventional whole-muscle dosing requires many superficial injections with attendant risks.
objectiveTo develop an anatomically guided protocol that targets motor-dense zones of the platysma, optimizing efficacy while reducing dose and complications.
methodsSihler-stained dissections mapped motor versus sensory innervation. Ultrasound-guided injections were performed in 40 patients, delivering 30-60 U BoNT-A per side at 15 sites concentrated in the upper two-thirds of the platysma and along the marginal mandibular border. Outcomes included band severity, jawline definition, adverse events, and cost.
resultsMotor end-plates clustered in the upper platysma; the lower third was largely sensory. Targeted injections produced a ≥ 2-grade reduction in dynamic bands in 92.5% of patients by week 4, maintained through week 12. Mean toxin use fell 35% versus historical whole-muscle protocols; bruising dropped to 5%, with no dysphagia or lower-face weakness. Treatment costs were proportionally lower.
conclusionsConcentrating BoNT-A in the motor-rich upper platysma under ultrasound guidance maximizes aesthetic improvements while minimizing dose, discomfort and adverse events. This neural distribution-based algorithm offers a safer, more economical alternative to conventional platysmal band treatment.
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Registered trials
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