Evidence map›Paper›PMID 40571662›Full record

ArticleJournal of Zhejiang University. Science. B2025

Single-cell transcriptome analysis reveals abnormal angiogenesis and placentation by loss of imprinted glutaminyl-peptide cyclotransferase.

Jing Guo, Jihong Zheng, Ruixia Li, Jindong Yao, He Zhang, Xu Wang, Chao Zhang

Abstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing GuoFundamental Research Center, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
Jihong ZhengFundamental Research Center, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
Ruixia LiObstetrics & Gynecology Hospital of Fudan University, Fudan University School of Medicine, Shanghai 200433, China.
Jindong YaoFundamental Research Center, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
He ZhangInstitute for Regenerative Medicine, Shanghai East Hospital, School of Life Science and Technology, Tongji University, Shanghai 200092, China.
Xu WangDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA. xzw0070@auburn.edu.
Chao ZhangFundamental Research Center, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Life Sciences and Technology, Tongji University, Shanghai 200092, China. zhangchao@tongji.edu.cn.

Funding

the Interdisciplinary Project in Ocean Research of Tongji University 2022-2-ZD-02the National Natural Science Foundation of China 32271165
6 · The paper itself

Abstract

Imprinted genes play a key role in regulating mammalian placental and embryonic development. Here, we generated glutaminyl-peptide cyclotransferase-knockout (

Indexed as

Neovascularization, PathologicPlacentationAngiogenesisAnimalsFemaleGene Expression ProfilingGenomic ImprintingMiceMice, KnockoutPlacentaPregnancySingle-Cell AnalysisSingle-Cell Gene Expression AnalysisTranscriptomeAngiogenesisGlutaminyl-peptide cyclotransferase-knockout(Qpct-/-) miceOvergrowthPlacentaSingle-cell sequencing

Identifiers

PMID40571662
PMCPMC12219499

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.