Evidence map›Paper›PMID 40571610›Full record

ReviewInternal medicine (Tokyo, Japan)2026

Ectopic Insulinoma in the Pyloric Antrum Portion of the Stomach: A Case Report and Review of the Associated Diagnostic Challenges.

Naohiro Sakamoto, Tsutomu Nishida, Masaya Hirano, Toshiki Noma, Yukiyoshi Okauchi, Hiroshi Imamura, Shiro Adachi, Hiromi Iwahashi

Abstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Naohiro SakamotoDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Tsutomu NishidaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Masaya HiranoDiabetes Center, Toyonaka Municipal Hospital, Japan.
Toshiki NomaDepartment of Gastroenterological Surgery, Toyonaka Municipal Hospital, Japan.
Yukiyoshi OkauchiDiabetes Center, Toyonaka Municipal Hospital, Japan.
Hiroshi ImamuraDepartment of Gastroenterological Surgery, Toyonaka Municipal Hospital, Japan.
Shiro AdachiDepartment of Pathology, Toyonaka Municipal Hospital, Japan.
Hiromi IwahashiDiabetes Center, Toyonaka Municipal Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ectopic insulinomas are rare neuroendocrine tumors that present with diagnostic challenges because of their atypical location. We report the case of a 64-year-old woman with recurrent hypoglycemia caused by an insulinoma originating from the gastric pyloric antrum. The diagnosis was confirmed through clinical assessment, biochemical testing, imaging studies, and a histopathological examination. Laparoscopic distal gastrectomy with D1 lymphadenectomy was performed to resolve the hypoglycemic episodes. This case highlights the importance of considering ectopic insulinomas in the differential diagnosis of unexplained cases of hypoglycemia, and it underscores the need for a multidisciplinary approach using advanced imaging and histopathological evaluations to make an accurate diagnosis and provide effective treatment.

Indexed as

InsulinomaPyloric AntrumStomach NeoplasmsDiagnosis, DifferentialFemaleGastrectomyHumansHypoglycemiaMiddle Agedectopic insulinomagastric insulinomainsulinneuroendocrine tumor

Identifiers

PMID40571610
PMCPMC12854957

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.