ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2025
Features of MR Imaging that Differentiate between Immunohistochemically Diagnosed Dedifferentiated Liposarcoma and Myxoid Liposarcoma.
Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Liposarcoma: State of the Art-A Scoping Review.Medical sciences (Basel, Switzerland) · 2026Article
- WCCAN: Windowed Cross-contrast Attention Network for Multi-contrast Brain MR Image Super-resolution.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Article
- Imaging Findings of Atypical Spindle Cell/Pleomorphic Lipomatous Tumors: A Case Series and Systematic Review.Cureus · 2025Article
- Commentary: Case Report: a giant liposarcoma of the spermatic cord.Frontiers in oncology · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
purposeThis study aimed to compare the differences in the imaging findings for dedifferentiated liposarcoma (DDLS) and myxoid liposarcoma (MLS).
methodsThe study included 30 patients with histopathologically confirmed DDLS and 13 patients with MLS. All DDLSs and MLSs were diagnosed immunohistochemically using MDM2 and DDIT3 staining, respectively. Conventional MRI, CT, and
resultsThe median age of patients with DDLS was higher than that of patients with MLS (74 vs. 46 years, P < 0.01). In 10 DDLSs and 7 MLSs with fatty areas, the well-differentiated liposarcoma-like fatty areas were more common in DDLS than in MLS (70% vs. 14%), whereas septal/linear fatty areas were less common in DDLS than in MLS (30% vs. 86%, P < 0.05). The T2-hyperintense area of non-fatty area was less common in DDLS than in MLS (50% vs. 92%, P < 0.05), and the tumor-to-muscle signal intensity ratio of non-fatty areas on T2-weighted images was lower in DDLS than in MLS (3.18 vs. 5.92, P < 0.01). Apparent diffusion coefficient value was lower in DDLS than in MLS (1.29 vs. 2.10 × 10
conclusionMRI features are valuable in differentiating MLS from DDLS. Younger age, septal/linear fatty areas, and high signal intensity of non-fatty areas on T2-weighted images were useful for diagnosing MLS.
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